UTI things to try and memorize

Question 1

48 hour rule

Answer 1

hospital aquired/nosomcomial

Question 2

Recurrent UTI

Answer 2

3 or more symptomatic episodes w/in one year

Question 3

Significant bacteruria

Answer 3

Greater than or equal to 10 to the fifth

Question 4

E. coli

UPEC

Answer 4

Gram negative

Question 5

Proteus mirabilis

Answer 5

urease producer

gram neg

Question 6

Klebsiella pneumoniae

Answer 6

gram neg

Question 7

Staph saprophyticus

Answer 7

urease producer

gram positive

Question 8

Only time women don’t have more UTIs than men

Answer 8

0-1 year

>50 yo (evens out)

Question 9

REFLUX:
Blocks flow of urine and promotes pyelo
Muscle tone reduction on ureter valves
STASIS:
Hormonal effects on persitalsis

Answer 9

Pregnancy!

Messes you up.

Question 10

Fimbrial lesions of E. coli:

Mannose sensitive

Answer 10

LOWER UTI - acute cystitis

Bind mannose residues on proteins of bladder mucosa, free mannose blocks binding

Question 11

Fimbrial lesions of E. coli:

P fimbria

Answer 11

A/w acute pyelonephritis
Bind to P blood group antigen on RBC and uroepithelial cells

*do not bind mannose

Question 12

2 toxins

Answer 12

Hemolysin
Endotoxin (LPS - gram neg)

Question 13

Siderophore

Answer 13

Aerobactin - scavenges iron

Question 14

Raises pH of urine by hydrolyzing urea to ammonia

Can cause struvite crystals

Answer 14

Urease enz

mirabilis and saprophyticus

Question 15

Capsular K antigen

Protects from phagocytosis

Answer 15

ONLY gram negative enterobacteriacea

Question 16

Descending bacteria (rare) indicates

Answer 16

Hematogenous and lymphatic source of infection (maybe sepsis)

Question 17

Urethritis
Bacteriuria
Pyuria

Answer 17

Cystitis, lower UTI

Question 18

Localized infection wtih systemic effects
May precipitate premature labor
*HALLMARK of flank pain**
CVA tenderness 
Fever

Answer 18

Pyelonephritis, upper UTI

Question 19

Criteria to dx UTI

Answer 19

+culture 10 to the 5 AND 10 to the 5 WBC
10 to the 2 w/ acute sx and pyuria
ANY CFU/ml from suprapubic aspiration or that has staph aureus