Viral Infections: Viral Hemorrhagic Fever

Question 1

Viral hemorrhagic fever is a ___ syndrome

Answer 1

Severe life-threatening multisystem syndrome

Question 2

Viral hemorrhagic fever causes shock from _____

Answer 2

Vascular dysregulation and damage

Question 3

Viral hemorrhagic fever is caused by which genera of virus?

Answer 3

4 genera of enveloped RNA viruses:

> Arenaviridae

> Filoviridae

> Bunyaviridae

> Flaviviridae

Question 4

Viral hemorrhagic fever has a mild disease presentation which includes the following:

Answer 4

> Fever

> Headache

> Myalgia

> Rash

> Neutropenia

> Thrombocytopenia

Question 5

Viral hemorrhagic fever starts in ___ host during cycle and ___ are incidental hosts

Answer 5

> Animal / insect host = rodents, mosquitoes, ticks

> Humans

Question 6

How is viral hemorrhagic fever transmitted?

Answer 6

Person to person spread such as Ebola, Marburg, and Lassa

Question 7

Give examples of hemorrhagic damage caused by viral hemorrhagic fever

Answer 7

> Endothelial cell damage

> Thrombocytopenia / Platelet dysfunction –> Petechiae

> Cytokine-induced disseminated intravascular coagulation (Where there is widespread clotting of blood) –> Consumption of clotting factors –> Severe bleeding

> Deficiency of clotting factors due to liver injury