Viral Infections

Question 1

Influezna Treatment

Answer 1

Neuramindase Inhibitors

Endonuclease Inhibitors

Question 2

Tamiflu Dosing

Answer 2

Treatment: 75mg Bid for 5 days
Prophylaxis: 75 mg daily for 10 days
Must be Greater than 12 yo

Question 3

Zanamivir (Relenza) importance

Answer 3

Cannot be used in patients with Lung conditions since it is inhaled
treatment greater than 7 yo
prophylaxis greater than 5 yo

Question 4

Endonuclease Inhbitor

Answer 4

Xofluza (Baloxavir)
Importance:
treatment and prophlyaxis is dependent on weight
40 to less than 80: 40mg once
greater than 80: 80mg once
Approved for greater than 12 yo

Question 5

Antivirals for Herpes Simplex

Answer 5

Acyclovir or Valacyclovir(Prodrug)
Caution with patients with renal impairment, elderly or those receiving nephrotoxic agents
Acyclovir Dose based on IBW even in obese

Question 6

Cold sore treatment

Answer 6

Abreva or Acyclovir Cream

Note that they are both applied 5 times daily but acyclovir can be applied to genital sores

Question 7

Herpes Zoster Treatment

Answer 7

Acyclovir for 7 days

Valacyclovir for 7 days

Question 8

Cytomegalovirus Treatment

Answer 8

Ganciclovir or Valganciclovir(prodrug)

Note of myleosupression, carcinogenic and teratogenic