Viral Hepatitis Flashcards

1
Q

Hepatitis A Overview

Including Transmission, Incubation Period, Chronic status and Vaccine

A

Transmission

  • Oral-faecal contact
  • Contaminated food and water

Incubation Period

  • 2-7 weeks
  • Average 4 weeks

Chronic Infection
- No

Vaccine
- Yes

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2
Q

Hepatitis B Overview

Including Transmission, Incubation Period, Chronic status and Vaccine

A

Transmission

  • Sexual
  • Blood-to-blood contact
  • Mother to baby

Incubation Period

  • 2-7 weeks
  • Average 4 weeks

Chronic Infection

  • Yes
  • Adults 3-5%
  • Children 95%

Vaccine
- Yes

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3
Q

Hepatitis C Overview

Including Transmission, Incubation Period, Chronic status and Vaccine

A

Transmission

  • Blood-to-blood contact
  • Mother to baby

Incubation Period

  • 4-12 weeks
  • Average 6 weeks

Chronic Infection

  • Yes
  • Approximately 75%

Vaccine
- No

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4
Q

Hepatitis D Overview

Including Transmission, Incubation Period, Chronic status and Vaccine

A

Transmission
- Blood contact (in association with Hep B)

Incubation Period
- 2-6 weeks

Chronic Infection
- Yes

Vaccine
- No

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5
Q

Hepatitis E Overview

Including Transmission, Incubation Period, Chronic status and Vaccine

A

Transmission
- Oral-faecal

Incubation Period
- 2-4 weeks

Chronic Infection
- No

Vaccine
- No

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6
Q

Serology Interpretation
HBsAg - negative
Anti-HBc - negative
Anti-HBs - negative

A

Susceptible

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7
Q

Serology Interpretation
HBsAg - negative
Anti-HBc - positive
Anti-HBs - positive

A

Resolved HBV infection

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8
Q

Serology Interpretation
HBsAg - negative
Anti-HBc - negative
Anti-HBs - positive

A

Vaccinated

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9
Q
Serology Interpretation
HBsAg - positive
Anti-HBc - positive
Anti-HBs - negative
IgM anti-HBc - positive
A

Acute HBV infection

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10
Q
Serology Interpretation
HBsAg - positive
Anti-HBc - positive
Anti-HBs - negative
IgM anti-HBc - negative
A

Chronic HBV infection

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11
Q

Viral Hepatitis Management

A

Simple management

  • Rest +++
  • Fluids
  • Antiemetics

Antiviral therapy for HCV

  • Pegylated interferon
  • With ribavirin - goal is to eradicate HCV RNA

In addition

  • Counselling
  • Alcohol & OCP avoidance
  • Symptom control
  • Dose adjustment of medications
  • Cirrhosis complication screening
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