VIH Flashcards

1
Q

Enzimas que permiten la transformacion del virion de VIH de ARN a ADN en el citoplasma del huesped

A

Transcriptasa inversa e integrasa

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2
Q

Proteina necesaria para que el VIH pueda penetrar en la celula

A

GP 120

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3
Q

Correceptores del VIH

A

CCR5 y CXCR4

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4
Q

Donde podemos encontrar el correceptor CCR5?

A

En los monocito-macrofagos

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5
Q

Donde podemos encontrar el correceptor CXCR4?

A

En los Linfocitos T CD4+

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6
Q

Tecnicas serologicas para diagnosticar el VIH

A

Elisa (inespecifica, muy sensible)

Western-Blot (confirmatoria)

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7
Q

Con cuantas copias se considera carga viral indetectable en VIH?

A

50 copias/ml

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8
Q

Prueba que utilizariamos para el diagnostico de VIH en un RN hijo de madre infectada

A

PCR

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9
Q

Causa mas frecuente de meningitis en pacientes con VIH

A

Cryptococcus neoformans

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10
Q

Germen que mas frecuentemente se asocia a neumonitis en px con VIH

A

Pneumocystis jiroveci - P. carinii

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11
Q

Cual es el cuadro clinico tipico de una neumonitis por P. Jiroveci en px con VIH?

A

Neumonia subaguda + disnea + fiebre + hipoxemia + infiltrados intersticiales

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12
Q

Cual conteo de CD4 predispone a infecciones por Pneumocystis en px con VIH?

A

<200 CD4

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13
Q

Cual conteo de CD4 predispone a infecciones por Cryptococcus en px con VIH?

A

<100 CD4

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14
Q

Tratamiento y profilaxis de neumonitis en VIH

A

Cotrimoxazol

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15
Q

Causa mas frecuente de convulsiones tras encefalopatia por VIH

A

Toxoplasma gondii

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16
Q

Infeccion secundaria del SNC mas habitual en los pacientes con SIDA

A

Toxoplasma gondii