Vestibular Schwannoma Flashcards
0
Q
CPA tumor DDX
A
85% VS
15% meningioma
1
Q
Most important sequence on MRI
A
T1 post (nasal mucosa lights up)
2
Q
Which vestibular nerve more commonly develops VS
A
Inferior
3
Q
Hitselberger sign
A
Dec sensation of EAC and concha from VS compression onto CN 7
4
Q
M/c site of origin
A
Laterally near scarpa ganglion (not at the glial-Schwann cell junction known as Obersteiner-Redlich zone)
5
Q
Can you die from VS?
A
Yes, from hydrocephalus
6
Q
Antoni A vs B
A
A: regions of compact spindle cells with whorls of palisading nuclei in rows (Verocay bodies)
B: less dense and more loosely arranged
7
Q
Immunohistochemical marker
A
S100 b Schwann cells are neural crest
8
Q
NF2 gene, protein
A
Gene: NF2
Protein: Merlin (cytoskeletal protein)
9
Q
Presentation
A
U/l auditory or vestib dysfnc in most 75% u/l tinnitus early U/l HL develops in 95% Only 5% p/w SSNHL Dysequilibrium is CC in only 10% Other CN deficits
