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LECOM Pharm 1-Liners > ** Very High-Yield ** > Flashcards

** Very High-Yield ** Flashcards

1
Q

Interaction with this drug requires dose reduction of 6-MP

A

Allopurinol

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2
Q

Antidote for tissue plasminogen activator (t-PA), streptokinase

A

Aminocaproic acid

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3
Q

Cheap wide spectrum antibiotic DOC of otitis media

A

Amoxicillin

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4
Q

Antidote used for organophosphate/anticholinesterase poisoning

A

Atropine, pralidoxime (2-PAM)

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5
Q

Vancomycin MOA

A

Binds D-Ala-D-Ala on murein monomers and prevent polymerization of the murein monomers

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6
Q

ACTH analog used for diagnosis of patients with corticosteroid abnormality

A

Cosyntropin

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7
Q

Agents used in treatment of carcinoid tumor

A

Cyproheptadine

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8
Q

1st generation antihistamine that is highly sedating

A

Diphendydramine

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9
Q

Common SE of spironolactone

A

Gynecomastia and hyperkalemia

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10
Q

MOA of fluoroquinolones

A

Inhibit DNA gyrase (topoisomerase II) and topoisomerase IV

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11
Q

Agent of choice for the treatment of hypothyroidism

A

Levothyroxine (T4)

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12
Q

Drug of choice for tx of pseudomembranous colitis

A

Metronidazole

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13
Q

Agents for reduction of postpartum bleeding

A

Oxytocin and ergonovine

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14
Q

Binds tubulin and prevents the disassembly of microtubules during the M phase of the cell cycle inducing mitotic arrest

A

Paclitaxel (taxol)

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15
Q

Antidote used for heparin toxicity

A

Protamine Sulfate

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16
Q

Selective estrogen receptor modulator (SERM) used for prevention of osteoporosis and currently being tested for treatment of breast cancer (Stars study)

A

Raloxifene

17
Q

Increase bone density, also being tested for breast CA tx.

A

Raloxifene (SERM-selective estrogen receptor modulator)

18
Q

5HT-1D/1B agonist used for migraine headaches

A

Sumatriptan, naratriptan, and rizatriptan

19
Q

Anti-estrogen used for estrogen receptor + breast cancer

A

Tamoxifen

20
Q

5HT-3 antagonist used in chemotherapeutic induced
emesis

A

Ondansetron, granisetron, dolasetron and palonosetron

LECOM Pharm 1-Liners (3 decks)

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