Venular Processes

Question 1

How are new blood vessels formed

Answer 1

• start off as small capillaries where blood travels through
• the capillaries primary cell type is endothelial cells which sprout from the capillary to form new blood vessels

Question 2

When does angiogenesis occur

Answer 2

• creation of a child’s circulatory system
• tumour formation
  -in tissues during Wound healing

Question 3

What is angiogenesis

Answer 3

The process of forming new blood vessels from pre existing ones
-this process rarely occurs because the cells in the blood vessels rarely divide

Question 4

Inducing angiogenesis

Answer 4

-need a stimulus E.g mechanically damaged tissues
-need expression of angiogenic molecules to initiate angiogenesis e.g VEGF

Question 6

Cascade of events

Answer 6

-angiogenic factor production e.g VEGF is released and binds on the epithelial cells receptors
- EC IS ACTIVATED
- EC PROLIFERATION
- directional migration
-ecm remodelling
-Tube formation
-loop formation
-vascular stabilisation