Inflammation 1

Question 1

Wound healing

Answer 1

A complex integrated sequence of cellular,
physiologic, and biochemical events initiated
by the stimulus of injury to tissue

Question 2

Healing process

Answer 2

The same events, in the same order, occur in
every healing process regardless of the tissue
type or the inciting injury

The body wants to limit the damage and restore the function

Question 3

Primary closure

Answer 3

The skin had the epidermis, dermis and fat and muscle
This can open so leaves a scar

Question 4

Secondary closure

Answer 4

A big gap happens due to injury so granulation tissue forms in the gap and eventually becomes a scar

Question 5

Neutrophils

Answer 5

•Protection against infection
•Intracellular products release
-free radicals
-cyclooxygenase products
-lipooxygenase products
-proteases

Question 6

Macrophages

Answer 6

•phagocytosis
•release cellular products
complement factors,
reactive oxygen metabolites,
growth factors,

Question 7

What are the 3 phases of wound healing

Answer 7

◼ Inflammatory Phase
◼ Proliferative Phase
◼ Remodeling Phase

Question 10

Inflammatory Phase

Answer 10

Hemostasis and Inflammation
•Days 0 - 6
•Exposed collagen activates clotting cascade
and inflammatory phase
•Fibrin clot = scaffolding and concentrate
cytokines and growth factors