Ventricular Septal Defect Flashcards

1
Q

Ventricular Septal Defect presentation

A

This patient has developed sudden shortness of breath. Examine his heart.

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2
Q

Clinical signs of Ventricular septal defect

A
  1. Thrill at the lower left sternal edge
  2. Auscultation:
    - Systolic murmur well localized at the left sternal edge with no radiation.
    - No Audible A2.
    - Loudness does not correlate with size (Maladie de Roger: loud murmur due to high-flow velocity through a small VSD).
    - If Eisenmenger’s develops the murmur often disappears as the gradient diminishes.
  3. Other associated lesions: AR, PDA (10%), Fallot’s tetralogy and coarctation
  4. Pulmonary hypertension: loud P2 and RV heave + cyanosis and clubbing (Eisenmenger’s)
  5. Endocarditis
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3
Q

Auscultation in VSD

A
  1. Systolic murmur well localized at the left sternal edge with no radiation.
  2. No Audible A2.
  3. Loudness does not correlate with size (Maladie de Roger: loud murmur due to high-flow velocity through a small VSD).
  4. If Eisenmenger’s develops the murmur often disappears as the gradient diminishes.
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4
Q

Causes of VSD

A
  1. Congenital
  2. Acquired (traumatic, post‐operative or post‐MI)
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5
Q

Investigation for VSD

A
  1. ECG: conduction defect: BBB
  2. CXR: pulmonary plethora
  3. TTE/TOE: site, size, shunt calculation and associated lesions
  4. Cardiac catheterization: consideration of closure
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6
Q

Management of VSD

A

Surgical (pericardial patch) or percutaneous (Amplatzer® device) closure of haemodynamically significant defects.

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7
Q

Associations with VSD

A
  1. Fallot’s tetralogy
  2. Coarctation
  3. Patent ductus arteriosus (PDA)
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8
Q

Fallot’s tetralogy

A
  1. Right ventricular hypertrophy
  2. Overriding aorta
  3. VSD
  4. Pulmonary stenosis
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9
Q

Blalock–Taussig (BT) shunts

A
  • Partially corrects the Fallot’s abnormality by anastomosing the subclavian artery to the pulmonary artery
  • Absent radial pulse and scar
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10
Q

causes of an absent radial pulse

A
  • Acute:
    1. Embolism,
    2. Dissection
    2. Trauma, e.g. radial artery sheath
  • Chronic: ABCT
    1. Atherosclerosis,
    2. Blalock-Taussig (BT) Shunts
    3. Coarctation,
    4. Takayasu’s arteritis (‘pulseless disease’),
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11
Q

Coarctation of Aorta

A

A congenital narrowing of the aortic arch that is usually distal to the left subclavian artery.

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12
Q

Clinical signs of Coarctation of Aorta

A
  1. Hypertension in right ± left arm (coarctation usually occurs between left common carotid and left subclavian arteries)
  2. Prominent upper body pulses, absent/weak femoral pulses, radiofemoral delay
  3. Heaving pressure loaded apex
  4. Auscultation:
    - Continuous murmur from the coarctation and collaterals radiating through to the back.
    - There is a loud A2.
    - There may be murmurs from associated lesions
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13
Q

Auscultation in Coarctation of Aorta

A
  1. Continuous murmur from the coarctation and collaterals radiating through to the back.
  2. There is a loud A2.
  3. There may be murmurs from associated lesions
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14
Q

Associations of Coarctation of Aorta

A
  1. Cardiac: VSD, bicuspid aortic valve and PDA
  2. Non‐cardiac: Turner’s syndrome and Berry aneurysms
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15
Q

Investigation of Coarctation of Aorta

A
  1. ECG: LVH and RBBB
  2. CXR: rib notching, double aortic knuckle (post stenotic dilatation)
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16
Q

Management of Coarctation of Aorta

A
  1. Percutaneous: endovascular aortic repair (EVAR)
  2. Surgical: Dacron patch aortoplasty
  3. Long‐term anti‐hypertensive therapy
  4. Long‐term follow‐up/surveillance with MRA: late aneurysms and recoarctation
17
Q

Patent ductus arteriosus (PDA)

A

Continuity between the aorta and pulmonary trunk with left to right shunt
Risk factor: rubella

18
Q

Clinical signs Patent ductus arteriosus (PDA)

A
  1. Collapsing pulse
  2. Thrill second left inter‐space
  3. Thrusting apex beat
  4. Auscultation: loud continuous ‘machinery murmur’ loudest below the left clavicle in systole
19
Q

Complications of Patent ductus arteriosus (PDA)

A
  1. Eisenmenger’s syndrome (5%)
  2. Endocarditis
20
Q

Management of Patent ductus arteriosus (PDA)

A

Closed surgically or percutaneously