Ventilator Flashcards
the first ventilators used ____ pressure. They were called _____
negative
the iron lung
The iron lung was developed to save victims of respiratory failure due to
polio
in positive pressure ventilation, the only connection between the patient and the machine is the _____
endotracheal tube
why we call them “agents” and not “gasses?”
administered as vapor, not gas
Vapor
a solution in liquid form dissipates or evaporates and releases molecules into the air around it
Vapor pressure
pressure exerted by a gas above a liquid in a sealed container
Strong intramolecular forces = _____ vapor pressure
lower
Weak intramolecular forces = ____ vapor pressure
higher
Water has ___ vapor pressure
lower
We can smell liquids that have (lower/higher) vapor pressure
higher
ie: acetone
(low/high) vapor pressure liquids easily give up their molecules to evaporation
high
Anesthetic agents have (lo/hi) vapor pressure.
high
Highest vapor pressure amongst anes. agents
Desflurane
We pressurize the agent ____ to ___ atm and heat it to ____ C
Des
2
40C (Barash: 39C)
principle of fluid dynamics that pulls the vapor molecules off the canisters and into the circuit
Bernoulli’s
Venturi Effect
The entrainment of fluid (gas or liquid) due to the drop in pressure
Bernoulli’s principle states that…
An increase in the speed of a fluid occurs simultaneously with a decrease in pressure or a decrease in the fluid’s potential energy
Venturi effect in the machine
(a drop in pressure will entrain gas/liquid)
-fresh gas flows over the top of the canister
-creates a - pressure grdnt
-pulls vapor up and out
why do we reach MAC faster if you turn your flows up at the beginning of the case?
Venturi effect
neg. pressure in vaporizer pulls vapor up and out of canisters
MAC of Desflurane
6.6%
most lipid insoluble of all the agents
Desflurane
lipid insoluble volatile agents
-body trying to push it back out through the lungs
-force it in by high inspired %
(why Desflurane the quickest on and quickest off)
quickest on and quickest off volatile agent
Des
populations is Desflurane good for
Quick cases
obese
Which patients is Desflurane bad for?
Long cases
reactive airways (asthma, smokers)
tachycardia
Desflurane settings
flows max: 1L/min
inspired percentage high: 12%+
will reach MAC in same time as Higher % and flows, minus the SEs
Sevoflurane MAC
1.8%
Most to least lipid sol
Iso
sevo
Des
least pungent of the agents
Sevo
“Sevo smells bessst”
“smell the sevo, it’s great!”
Sevo, sweetie
agent of choice for inhalational inductions
Sevo
b/c she smell gewd
Flow requirements for ____ are 2L/min due to risk of forming _____
Sevo
Compound A
“sevo serving us compound A”
populations is Sevoflurane good for?
Reactive airways
case that requires high flows (bronchs)
LMA (not paralyzed = higher risk of bronchospasm)
most lipid soluble of the agents
Isoflurane
(soluble/insoluble) agents take the longest to go on and to come off
soluble
Higher b:g = slower
Iso (highest b:g) is slowest
(remember, when talking about agents, “in/soluble” means water/blood solubility)
What happens to insoluble agents in the body?
body sequesters it in the fat and then rereleases it into the plasma
MAC of Isoflurane
1.17%
What cases is Isoflurane most suited for
remain intubated and ICU admit
lasts longer = anesthesia “for the road”
most neuroprotective of the agents
Iso
I so save your brain
All agents reduce ___, which is good for the brain, but reduce ___ , which is bad for the brain
cerebral metabolic rate
cerebral blood flow
What makes Iso more neuroprotective?
reduces Cereb metab rate more & blood flow less
(all agents:
reduce CMR= good
reduce CBF = bad)
When to use Iso
hemorrhagic stroke
head trauma w/ crani for hematoma evac
and other pts that always go direct to ICU on vent
basic components of air
21% oxygen
78% nitrogen
and other stuff we dc about rn
inspiring 75% oxygen & four 4.5 % Desflurane
where’s the rest?
We’re giving air (78% Nitrogen)
remaining % = nitrogen
inspired and expired gasses here are measured in
%s
Flows are measured in
L/min
Six percent of 0.5 liters is the same DOSE as ___ percent of 2 liters
six
same percentage, just takes less amount
low-flow anesthesia allows us to use less agent at ____
steady state
Which is more expensive?
TIVA
inhaled agents
TIVA
Which is worse for the environment?
low flow anesthesia
TIVA
low flow anesthesia
primary benefit to low-flow delivery
economic
(earth, you’re second I guess lol)
primary downside of low flow anesthesia
changing dose takes longer
How to best change dose in low-flow anesthesia
temporarily raise your flows
or
inspired % really high or really low
after desired MAC is reached, put settings back how they were
etCO2 capnography
normal range
30-40
NOT 35-45; thats PCO2 (PaCO2) on ABGs
capnography is measured in
pressure mmHg
_____ is about 5 points higher than ____
PaCO2 (listed as PCO2 on ABG)
>
etCO2
T/F
The gap in PCO2 (PaCO2) and etCO2 is due to dead space, especially from the vent circuit.
False
gap exits b/c gases use differences in partial pressures to diffuse (gas exchange)
etCO2 sensor on circuit so close to mouth that dead space is not a significant contributor
T/F
the vent circuit contributes greatly to dead space, which increases the gap between PCO2 and etCO2
False
etCO2 sensor on circuit so close to mouth that dead space is not a significant contributor
T/F
PACO2 measures CO2 in the arteries
False
PACO2 = Alveoli
PaCO2 = arteries
(“Al” both tall; “ar” both short)
PCO2 NR
35-45
(etCO2 30-40)