Ventilation & diffusion Flashcards

1
Q

What are the conducting airways?

A

Divisions 1-16 - dead space - bulk flow - no gas exchange

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2
Q

What are the respiratory airways?

A

Divisions 17-23 - alveoli for gas exchange via diffusion

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3
Q

What is hypoxic constriction?

A

There is a dense capillary network around the alveoli. If there is low o2 in certain alveoli, vessels can constrict and divert blood to areas of high o2

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4
Q

What is the diffusion barrier?

A
  • Alveolar wall
  • Epithelial cells of alveolus
  • Tissue fluid & connective tissue
  • Endothelial cell of capillary
  • Plasma
  • Red cell membrane & cytoplasm
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5
Q

When has o2 fully saturated Hb?

A

When its 25% along capillary

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6
Q

What is tidal volume?

A

Volume of air moved in & out of lungs in normal breathing

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7
Q

What is the inspiratory reserve volume?

A

Extra volume over that can be breathed in at rest

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8
Q

What is the expiratory reserve volume?

A

Extra volume over that can be breathed out at rest

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9
Q

What is residual volume?

A

Volume left in lungs following max expiration

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10
Q

What is total lung capacity?

A

(TV+IRV+ERV+RV)

Total volume of air present in lungs at end of max inspiration

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11
Q

What is inspiratory capacity?

A

(IRV+TV)

Biggest breath that can be taken from resting expiratory level

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12
Q

What is vital capacity?

A

(IRV+TV+ERV)

Measured from max inspiration to max expiration (biggest breath)

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13
Q

What is functional residual volume?

A

(ERV+RV)

Volume of air remaining in the lungs at the resting expiratory level

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14
Q

What is total/minute ventilation?

A

Amount of air moved in and out of lungs per min.

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15
Q

What is the alveolar ventilation rate?

A

The amount of air that actually reaches the alveoli per minute

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16
Q

What is the V/Q ratio?

A

Ratio of ventilation (V) to perfusion (Q) - ideally is 1.

17
Q

How does V/Q differ throughout the lung?

A

V/Q decreases as go down lung as base is over-perfused

18
Q

What happens when there is a V/Q mismatch of the whole lung?

A

Hypoxaemia