Vasoactive Peptides

Question 1

transmitters in the autonomic and central nervous systems

Answer 1

Vasoactive peptides

Question 2

angiotensin II, VD or VC?

Answer 2

Vasoconstrictor

Question 3

vasopressin, VD or VC

Answer 3

Vasoconstrictor

Question 4

endothelins VD, or VC?

Answer 4

Vasoconstrictor

Question 5

neuropeptide Y VD, or VC

Answer 5

Vasoconstrictor

Question 6

urotensin VD or VC

Answer 6

Vasoconstrictor

Question 7

(bradykinin and related kinins VD or VC

Answer 7

Vasodilator

Question 8

natriuretic peptides,

Answer 8

Vasodilator

Question 9

vasoactive intestinal peptide

Answer 9

Vasodilator

Question 10

substance P

Answer 10

Vasodilator

Question 11

neurotensin

Answer 11

Vasodilator

Question 12

calcitonin
gene-related peptide

Answer 12

Vasodilator

Question 13

adrenomedullin

Answer 13

Vasodilator

Question 14

Inactive form of angiotensin 1

Answer 14

angiotensinogen

Question 15

Modulators of renin release aside from synthesis of renin

Answer 15

1. Macula densa
2. Renal baroreceptor
3. Sympathetic NS
4. Angiotensin
5. Intracellular signaling pathways
6. Pharmacologic alteration of renin release

Question 16

A specialized region of distal convoluted tubule

Answer 16

Macula Densa

Question 17

where renin is released/regulated

Answer 17

Macula densa

Question 18

Relationship between NACL deliver/concentration and renin release

Answer 18

Inversely proportional

Question 19

Prostaglandin E2 and Nitric Oxide

Answer 19

Stimulate renin release

Question 20

Adenosine

Answer 20

Renin release inhibitor

Question 21

If NACL is low, filtrate flow or urine output is?

Answer 21

reduces; low

Question 22

Renal vascular baroreceptor relationship with renal artery pressure and renin release

Answer 22

Inverse relationship

Question 24

Low BP and renin release relationship

Answer 24

Inverse

Question 25

Renin, a vasodilator or vasoconstrictor?

Answer 25

Vasoconstrictor

Question 26

Enzyme which converts Angiotensin I to Angiotensin II

Answer 26

Converting enzyme

Question 27

Angiotensin II, vasodilator or vasoconstrictor?

Answer 27

POTENT VASOCONSTRICTOR

Question 28

ANG II action on renin release

Answer 28

Inhibit

Question 29

2nd messengers/ intracellular messengers

Answer 29

cAMP, cGMP, and free cytosolic Calcium (Ca2+) concentration

Question 30

cAMP and renin relationship

Answer 30

directly proportional

Question 31

adenyly cyclase and renin relationship

Answer 31

directly proportional

Question 32

Drugs that alter renin release

Answer 32

1. Vasodilators 2. B-Adrenoceptor agonists 3. A-adrenoceptor antagonists 4. Phosphodiesterase inhibitors 5. most diuretics 6. anesthetics

Question 33

most important substrate of ACE

Answer 33

ANG I

Question 34

Ace Inhibitors

Answer 34

captopril enalapril lisinopril

Question 35

Bradykinin MOA

Answer 35

activates cough reflex

Question 36

ANG II mechanisms in raising blood pressure (4)

Answer 36

1. Vasoconstriction 2. Aldosterone release 3. ADH Release 4. cell growth

Question 37

Drugs that interfere with renin release

Answer 37

Propanolol Ace inhibitors

Question 38

ANG receptor blockers

Answer 38

Losartan Olmesartan Valsartan Azilsartan Condesartan Telmisartan Irbesartan