Vasoactive drugs Flashcards
parasympathetic or sympathetic?
acetylcholine
parasympathetic
parasympathetic or sympathetic?
epinephrine
sympathetic
parasympathetic or sympathetic?
dobutamine
sympathetic
parasympathetic or sympathetic?
dopamine
sympathetic
parasympathetic or sympathetic?
phenylephrine
sympathetic
parasympathetic or sympathetic?
ephedrine
sympathetic
what to a1 receptors do?
vasoconstriction of peripheral blood vessels
what to beta 1 receptors do?
increases HR and contractility
(one heart)
what do beta 2 receptors do?
vasodilation and bronchodilation
what does dopamine do?
peripheral vasodilation
what do vasopressors do?
cause ARTERIOLE vasoconstriction and increase BP
what do inotropes do?
affects heart contractility
what do chronotropes do?
affects HR
what do dromotropes do?
affects cardiac conduction
symptoms of peripheral extravasation
burning
pain
edema
erythema
stinging
symptoms of central venous catheter extravasation
shoulder, neck, chest pain
cough
chest palpitations
fluid wave in chest or neck
Interventions to when extravasated
- notify MD
- administer phentolamine & topical nitroglycerin
DOPAMINE
a1
B1
B2
Heart rate
Contractility
Vasoconstriction
a1 - ++
B1 - ++++
B2 - ++
Heart rate - +++
Contractility - +++
Vasoconstriction - 0
DOBUTAMINE
a1
B1
B2
Heart rate
Contractility
Vasoconstriction
a1 - +
B1 - ++++
B2 - +++
Heart rate - ++
Contractility - +++
Vasoconstriction - 0
NOREPINEPHRINE
a1
B1
B2
Heart rate
Contractility
Vasoconstriction
a1 - ++++
B1 - ++
B2 - 0
Heart rate - +
Contractility - ++
Vasoconstriction - ++++
EPINEPHRINE
a1
B1
B2
Heart rate
Contractility
Vasoconstriction
a1 - ++++
B1 - ++++
B2 - +
Heart rate - +++
Contractility - +++
Vasoconstriction - +++
phenylepphrine
a1
B1
B2
Heart rate
Contractility
Vasoconstriction
(doesn’t affect the heart)
a1 - ++++
B1 - 0
B2 - 0
Heart rate - 0
Contractility - 0
Vasoconstriction - ++++