Vasculitis Flashcards
1
Q
What is the most common form of systemic vasculitis in adults?
A
Giant cell (Temporal) Arteritis - painful temporal artery Transmural inflammation - multi-nucleated giant cells
2
Q
Takayasu arteritis affects what arteries and which populations?
A
Pulmonary arteries 50% - large
Japanese women
3
Q
What two types of vasculitis affect the medium sized vessels?
A
- Polyarteritis Nodosa
2. Kawasaki Syndrome
4
Q
What are characteristics of polyarteritis nodosa?
A
- Renal and visceral arteries (spares lungs)
- All stages of inflamm/fibrosis exist
- Young adults - 30% Hep B Ag+
- Necrosis w/ karyorrhexis
5
Q
What is Kawasaki Syndrome
A
- Often coronary arteries w/ aneurysm
- 80% <4 yo in Japan
- Aneurysms
6
Q
What types of vasculitis affect small vessels?
A
- Microscopic polyangiitis (leukoclastic vasculitis)
- Wegener Granulomatosis
- Churg-Strauss Syndrome (allergic granulomatosis & angiitis)
- Thromboangiitis Obliterans (Buerger disease)
- Raynaud
7
Q
Which type of vasculitis is MPO-ANCA+
A
Microscopic Polyangiitis
8
Q
Which type of vasculitis is PR3-ANCA+
A
Wegener Granulomatosis
