Vasculitides

Question 1

Asian
Weak upper extremity pulses
Arthritis
Myalgias

(Dx, path, tx)

Answer 1

Takayasu arteritis (Large vessel)

Granulomatous thickening of aortic arch
Incr ESR

Tx steroids

Question 2

Middle aged man
Hep B pos
Melena
Neuro damage

(Dx, path, tx)

Answer 2

Polyarteritis nodosa (medium vessel)

Transmural inflammation w/ fibrinoid necrosis
(usually renal vessels - microaneurysms)

Tx steroids or cyclophosphamide