Vascular PP Flashcards
2 aspects that the extent of perioperative monitoring should be based on?
type of surgery and presence of coexisting disease
3 ways to assess cardiac function in vascular surgery patients?
TEE, EKG, PA cath
Does PAC monitoring affect length of stay or mortality in vascular patients?
no
When comparing vascular patients who had a PA cath versus those who did not, the PA cath group had higher rates of what 3 complications?
pulmonary embolism, pulmonary infarction, and hemorrhage
What procedures warrant routine use of PACs according to the ASA?
none
Patients with HTN or angiopathology rely on what to perfuse their vital organs>
increased mean arterial pressures
Patients with HTN or angiopathology require lower or higher pressures to maintain autoregulation?
higher
What is the most common cause of occlusive disease in arteries of lower extremities?
atherosclerosis
The short and sweet 3 step pathophysiology summary of how plaques affect arteries?
- plaque formation 2. thrombosis 3. aneurysm formation
4 symtpoms associated with peripheral occlusive disease?
gangrene, impotence, ulcers, claudication
Plaque is made up of what substances?
cholesterol, fat, Ca, fibrin, cellular waste products
Mortality rates for PVD at 5 years and 10 years, respectively?
30%; 70%
The extent of disability in PVD patients is influenced?
collateral blood flow
What is responsible for activating the clotting system in PVD?
inflammatory process
Target heart rate for beta blocker therapy in PVD patients?
50-60
Beta blocker therapy is recommended for PVD patients at risk for what 2 things?
MI, ischemia
5 effects on the pulmonary system that epidurals have?
Decreased effect on FVC, FEV1, and PEFR, Decreases ventilation perfusion mismatch, Improves atrioventricular oxygen differentiation, Decreases pulmonary postoperative complications, Decreased incidence of thromboembolism
2 effects that epidurals have on the renal system?
- Increases blood flow in the renal cortex
* Decreases renovascular constriction
2 effects that epidurals have in the geriatric population?
decreased stress and improved post op mental function
In regards to extubation and pain control how does epidural anesthesia affect those 2?
earlier extubation and improved pain control
What effects does epidural anesthesia have on the heart?
Decreases MVO2 demand & afterload, increases endocardial blood flow at ischemic zones, increased hemodynamic stability (?), Decreases GA medication usage, improves blood flow to lower extremities
7 things inhibited by epidurals?
surgical stress response, epinephrine & cortisol release (not sure if good or bad), hyperglycemia (good), lymphopenia, inflammatory mediator release, nitrogen sparing, blocks sympathetic tone
3 risks possible when having surgery on the aorta?
large intraop blood loss, renal failure, paralysis
An EF less than what percentage proves to be risky when having aortic surgery?
30
3 screening tools to diagnose AAA?
MRI, CT, ultrasound
Primary goal of preoperative period for AAA?
restore intravascular volume/fluid load
Blood products to have available for AAA surgery?
PRBC x 2, FFP, platelets
When does heparinization occur during AAA repair?
before occlusion
Renal prophylaxis during AAA repair can be completed with?
mannitol
Abdominal aortic aneurysm repair can be done using which 2 approaches?
transperitoneal or anterolateral
For an abdominal aortic aneurysm repair, what are the 3 locations the clamp can be placed?
supraceliac, suprarenal, infrarenal
There is less effect on LV afterload when the clamp is placed where in AAA surgery?
farther distally
The aortic cross clamp causes what to happen to BP above and below clamp?
above- HTN; below- hypotension
What happens to MAP and SVR during aortic cross clamping? What happens to PAW?
increase; increase PAW
What affect does aortic cross clamping have on afterload and wall tension?
increases both
Why may aortic cross clamping cause issues in the ischemic heart?
because aortic cross clamping increases afterload and wall tension
The hemodynamic effects of aortic cross-clamping depend on what 3 things?
the application site along the aorta, the patient’s preoperative cardiac reserve, and the patient’s intravascular volume
Most common site for aortic cross clamping?
infrarenal
What two systems are involved with aortic cross clamping?
SNS, RAAS
5 metabolic changes which occur from aortic cross clamping?
increased lactic acid, release of arachidonic acid, thromboxane A2, cyclo oxygenase inhibitors, increased epi and norepi levels
How do beta blockers help w the metabolic changes associated with aortic cross clamping?
as a result of aortic cross clamping, epinephrine and norepinephrine release are increased and stimulate myocardial β1-receptors that can increase heart rate and myocardial oxygen demand
This is a metabolic change associated with the decrease in myocardial contractility and cardiac output during aortic cross clamping?
thromboxane A2
5 symptoms common with mesenteric traction syndrome?
decreases in blood pressure and SVR, tachycardia, increased cardiac output, and facial flushing
These mediators are thought to be responsible for the tachycardia, elevated temp, leukocytosis, and fluid sequesteration during surgery?
TNF, IL-6, catecholamines, cortisol
The hemodynamic instability that may ensue after the release of an aortic cross-clamp is called?
declamping shock syndrome
What happens to the SVR, vessel tone, afterload, preload, CO, and myocardial tone in declamping shock syndrome?
all decrease and the vessel tone dilates and blood is directed to the dilated vasculature
This is paramount in providing circulatory stability before release of the aortic clamp?
Restoration of circulating blood volume
What three things influence the magnitude of circulatory instability after undoing the aortic cross clamp?
site and duration of cross-clamp application, gradual release of the clamp
What does decreased myocardial contractility do to total body oxygen consumption? What can the CRNA do to counteract decreased myocardial contractility during AAA repair?
increase; decrease vasodilators
What does decreased CVP do to prostaglandin levels?
decrease