OLV Flashcards
Ventilation is sum of all inhaled or exhaled gasses in one min?
exhaled
Type of dead space that is nonresp airways?
anatomic dead space
Type of dead space that is alveoli that are not perfused?
alveolar dead space
What is the sum of anatomic and alveolar dead space?
physiologic
What is the typical dead space in most adults in upright patient? And it is mostly what type of dead space?
150 mL; 2mL/kg; anatomic
How can you grossly estimate anatomic dead space?
weight of individual in pounds is roughly equivalent to dead space in mL
Right and left lung receive what % each of ventilation?
right lung- 53%; left lung- 47%
Are the upper or lower areas better ventilated?
lower
Why are the lower areas of lungs better ventilated?
gravitationally induced gradient in intrapleural pressure and therefore transpul pressure
What does a higher transpulmonary pressure in the upper part of the lungs mean for inspiration?
the alveoli in the upper lungs are near maximally inflated and relatively non compliant so they undergo little expansion during inspiration
What happens to the smaller alveoli in dependent areas during inspiration?
they have a lower transpulmonary pressure, are more compliant, and undergo greater expansion
Laminar flow resistance is proportional to? And which law is this?
viscosity x length of conduit divided by radius to 4th power; Poiseulle’s
Flow is proportional to?
change in pressure x radius 4th power divided by viscosity times length
Halving the radius does what to flow?
flow is 1/16 what it was
Is pulmonary blood flow uniform?
no
One example where zone 1 would be present?
pulmonary hypotension
What are the characteristics of the pressures in Zone 1?
pulmonary alveolar > pulmonary artery > pulmonary vein
How are the capillaries in zone 1?
capillaries are depressed, blood flow is impeded
Why is vascular resistance increased in zone 1?
apical alveoli are inflated
What is the net result as far as ventilation and perfusion in zone 1?
ventilation without perfusion
What do the capillaries do in zone 2?
flutter open and closed in inspiration and expiration
What are the pressures in zone 2?
pulmonary artery > alveolar > venous
How is blood flow determined in zone 2?
pressure gradient between arterial and alveolar pressures
How are the pressures related in zone 3?
pulmonary artery > pulmonary vein > alveolar pressure
How is flow determined in zone 3?
arterial venous pressure differences
Where should the tip of the swan be?
zone 3
2 examples where zone 4 is present?
ARDS, pulmonary edema
What are the pressure relationships in zone 4?
interstitial pressure > venous and alveolar pressure
How do you determine blood flow in zone 4?
pulmonary artery minus pulmonary interstitial fluid gradient
Where is pleural pressure least negative?
base of lung
3 other characteristics of base of lung besides pleural pressure being least negative?
alveoli most compressed, most compliant, smallest volume
Where is pleural pressure most negative in upright person?
apex