vascular pathology

Question 1

what are the two disorders with p-ANCA

Answer 1

micoscopic polyangiitis and churg-stress.

Question 2

henoch schonlein purpura

Answer 2

vasculitis due to IgA immune complex deposition. most common vasculitis in children. presents with palpable purpura in the skin on the buttocks and legs. IgA nephropathy. usually follows upper respiratory tract infection

Question 3

poly arteritis nodosa

Answer 3

necrotizing vasculitis involving most organs. lungs are spared
presents in young adults as HTN, abdominal pain and melena, neurologic disturbances, skin lesions, associated with HBsAg. string of pearls lesions.

Question 4

kawasaki

Answer 4

asian children <4. fever conjunctivitis, erythematous rash of the palms and soles. enlarged cervical lymph. coronary artery involved. thrombosis and MI. aneurysm and rupture. treat with aspirin.

Question 5

microscopic polyangiitis

Answer 5

lung and kidney. similar to WG. P-ANCA. no granuloma.

Question 6

churg-straus

Answer 6

necrotizing granulomatous vasculitis with eosinophils. involves multiple organs, especially the lungs and heart. asthma and peripheral eosinophilia. P-ANCA correlate with disease

Question 7

risk factors for HTN

Answer 7

age, race, obesity, stress, lack of physical activity, high-salt diet.