Vascular pathologies Flashcards
What does P-ANCA refer to in polyarteritis nodosa?
perinuclear pattern of antineutrophil cytoplasmic antibodies
What are the symptoms of Buerger’s disease?
intermittent claudication, superficial nodular phlebitis, cold sensitivity, severe pain in affected part -> may lead to gangrene
What is the most likely location of atherosclerosis?
abdominal aorta, coronary artery, popliteal artery, carotid artery
A patient present with cotton-wool spots, microaneurysms, pericarditis, myocarditis, and palpable purpura. Most likely dx:
polyarteritis nodosa
What is the MC site for berry aneurysms?
bifurcation of anterior communicating artery (circle of Willis)
T/F: atherosclerosis is a disease of small-sized arteries
F
What antibody is associated with this polyarteritis nodosa?
P-ANCA
DVT often presents with Virchow’s triad. Name the three features of this triad.
stasis, hypercoagulability, endothelial damage
Name the term that describes hyperlipidemia that causes a lipid deposit in tendons, esp. the achilles.
tendinous xanthoma is a lipid deposit in the tendon dt hyperlipidemia
In polyarteritis nodosa what viral infection is found in 30% of patients?
hepatitis B
Which vessels are affected by polyarteritis nodosa?
small to medium-sized muscular arteries, renal and visceral vessels
Name the three diseases that are associated with berry aneurysms.
adult polycystic disease, Ehlers-Danlos syndrome and Marfan’s disease
Temporal arteritis primarily affects whom?
elderly females
Polyarteritis nodosa primarily affects whom?
young males
What is the term given to a plaque or nodule composed of lipid-laden histiocytes in the skin, esp. eyelids?
xantholasma
What is the most effective treatment for Buerger’s disease.
quitting smoking
A patient presents with unilateral HA, jaw claudication and impaired vision. What is the most likely diagnosis?
temporal arteritis
Which additional syndrome can affect patients with temporal arteritis?
polymyalgia rheumatica
What is the term that describes the first grossly visible lesion in the development of atherosclerosis.
fatty streak
Temporal arteritis is AKA?
giant cell arteritis
A patient has a stroke after incurring multiple long bone fractures from trauma stemming from a MVA. Most likely cause of stroke:
fat emboli
What is the term given to a lipid deposit in the cornea associated with hyperlipidemia?
corneal arcus
Who suffers from Buerger’s disease?
young males, heavy smokers
List 7 common symptoms of polyarteritis nodosa.
fever, wt loss, malaise, abdominal pain, HA, myalgia, HTN
Thromboangiitis obliterans is AKA __
Buerger’s disease
Temporal arteritis usually affects what vessels?
medium and small arteries (usu carotid branches)
