Vascular Overview Flashcards
what is an aneurysm
Degeneration / weakening of arterial wall
Risk of rupture in intraluminal pressure > tensile strength of vessel wall
pathophysiology of _
decrease blood flow to extremity / organ secondary to formation of atherosclerotic plaques
Stenosis
decreased blood flow
decreased pressure
what is atherosclerosis
Accumulation of lipids around heart and major vessels
consequences of atherosclerosis
Hardening of vessels’
Integrity of endothelium
Narrowing & stenosis
Altered haemodynamics
Changes Intima + Media layers of vessel
risk factors of atherosclerosis
Genetics
Smoking
Diabetes
Hypertension
Obesity
Diet
list stages of atheroslcerosis
- build up of fibrous tissue surrounded by layer of cholesterol and lipid
causes changes in initima and media - clacification - calcification of border surrounding fibrous tissue
- haemorrhage
- ulceration - initima layer blood vessel bursts
- thrombosis
peripheral vascular disease symptoms
Pain / cramps LL - walking / exercise / rest
Intermittent claudication
Numbness or coldness feet
Discoloration toes cyanosis / pallor
Tingling & weakness
Infection
what causes pain/cramps of patient with peripheral vascular disease when walking/exercising
if there is an obstruction of blood vessel cannot excrete metabolic byproducts
symptoms on activity of intermittent claudication
Increased requirements of exercising muscle
Insufficient blood supply through narrowed vessel Symptoms produced by significant narrowing of arteries supplying limb
what is critical limb ischaemia
Persistent recurring pain requiring regular analgesia > 2/52
Ulceration or gangrene foot
Absent peripheral pulses
90% require surgical
gangrene definition
the destruction of living tissue due to obstruction of the blood and oxygen supply.
what bacteria causes gangrene
Clostridium (gas gangrene) or a combination of streptococci and staphylococci.
causes of dry gangrene
caused by gradual loss of blood
Causes
Diabetes
Atherosclerosis
Frostbite
what is dry gangrene
Skin painful / dark
Dead skin dry & drops off
Not life threatening
describe moist gangrene
More serious - fatal
Loss of blood supply
Dead cells leak fluid
Affected tissue becomes moist
Bacteria flourish
Skin swollen / blisters
Can spread quickly
what is gas gangrene
Most deadly form
Occurs in wounds affected by bacteria
Low O2 environment
Release of gas / poisons into body
Fever / brown pus gas bubbles
Rapid death
abdominal aortic aneurysm
Localised enlargement lumen abdominal aorta
Pulsatile swelling abdomen
how is abdominal aortic aneurysm monitored
use ultrasound
above 4cm may rupture
possible complications of diabetes
Small vessel damage
Retinopathy
Renal failure
Peripheral neuropathy
Sensory deficits hands / feet
PVD / Small artery disease
Ischaemia
what is varicose veins
Enlarged dilated tortuous veins in the lower limb
mechanism of varicose veins
Valve failure venous hypertension venous ulceration
investigation of veins
venography
management of varicose veins
Compressive stockings
Endovenous laser ablation
chronic venous insufficiency
Lower limb venous return impaired
causes of chronic venous insufficiency
Venous hypertension
Swelling & ulceration
Varicose ulcer
thrombophlebitis
Saphenous veins often associated with varicosities
DVT
Thrombus forms in vein
Secondary inflammation