Vascular Neurology Flashcards
4 classes of ischemic stroke
transient ischemic attack (TIA)
reversible ischemic neurologic deficit
evolving stroke
completed stroke
TIA vs. stroke
main difference is in DURATION of symptoms
TIAs usually last a few minutes to less than 24 hours
blockage of blood flow does not last long enough to cause permanent infarction
Why are TIA symptoms transient
reperfusion occurs (either due to collateral circulation or break up of embolus)
Etiologies of TIA
embolic (most common)
but transient hypotension 2/2 carotid artery stenosis (>75% occlusion) can also cause
TIA increases risk for…
STROKE in coming months
10% per year and 30% 5- year risk of stroke
risk factors for ischemic stroke
2 MOST IMPORTANT = age and HTN
others - smoking, DM, hyperlipidemia, afib, CAD, fmaily hx of stroke, PREVIOUS STROKE/TIA, carotid bruits
risk factors for stroke in younger patients
OCP use hypercoagulable states (protein C/S def, APA syndrome, cocaine/amphetamines, polycythema vera, sickle cell
transient, curtain like loss of sight in ipsilateral eye due to microemboli to the retina
amaurosis fugax (example of TIA)
common sources of emboli that cause stroke
heart (mural thrombus from afib)
internal carotid artery
aorta
paradoxical stroke (ASD, patent foramen ovael, pulmonary AV fistula)
thrombotic strokes occur due to atherosclerotic plaques in which arteries typically
large arteries of neck (carotid artery usu. at bifurcation of common carotid)
medium sized arteries of brain; i.e. middle cerebral artery MCA)
where do you typically see lacunar strokes
in small vessels of brain
usually affects subcortical structures (basal ganglia, thalamus, itnernal capsule, brainstem)…NOT CORTEX
how to evaluate for source of embolic stroke
echocardiogram
carotid doppler
ECG, holter monitoring
predisposing factors for lacunar stroke
hx of HTN!
DM also important risk factor
symptoms of vertebrobasilar arterial insufficiency
dizziniess, double vision, vertigo, numbness of ipsilateral face and contralateral limbs, dysarthria, hoarsness, dysphagia
caused by decreased perfusion in posterior fossa
subclavian steal syndrome
stenosis of subclavian artery proximal to origin of vertebral artery - exercise of left arm causes reversal of blood flow down the ipsilateral artery to fill the subclavian artery distal to stenosis because it cannot supply adequate blood to left arm; leads to decreased cerebral blood flow “stolen” from basilar system
BP in left arm is less than right arm; decreased pulses in left arm
subclavian steal
treatment for subclavian steal syndrome
surgical bypass
stroke with contralateral lower extremity and face
ACA
stroke with aphasia, contralateral hemiparesis
middle cerebral artery
dizziness, double vision, numbness of ipsilateral phase, contralaterla limbs, dysarthria, hoarseness, dysphagia, projectile vomiting, headahces, drop attacks
vertebrobasilar system
pure sensory deficit
thalamus
pure motor hemiparesis
internal capsule
alexia without agraphia
left PCA
patient presents to ED with stroke like symptoms…what to do and in what order
1) non contrast CT head
2) ECG, chest radiograph
3) CBC, plts
4) PT/INR
5) electrolytes
6) glucose
7) bilateral carotid ultra sound
8) echocardiogram
how do ischemic strokes look on non contrast CT?
dark area