Vascular Flashcards
1
Q
Bruising, rash, epistaxis + non blanching rash in 50Y F
A
ITP
2
Q
Causes of low platelet
A
Alcohol B12/folate Heparin induced Immune ADAMST3 deficient = TTP
3
Q
Management of ITP
A
Steroid
rituximab
IV Ig
Splenectomy
4
Q
Causes of abnormal prolonged bleeding
A
Thrombocytopenia
VW disease
Haemophilia A/B
DIC
5
Q
Management of VW disease
A
Desmopressin
VW factor
Factor VIII infusion
6
Q
Haemophilia A and B factor
A
A= VIII B= IX
7
Q
Polycythaemia Vera
A
Ruddy Splenomegaly Thrombocytosis Itch Bruise Sweating Conjunctival plethora
8
Q
Cells and mutation in Polycythaemia Vera
A
Erythroid cells
JAK2
9
Q
Management of PV
A
Venesection
Aspirin
Chemo
10
Q
What can myeloproliferative conditions transform to
A
AML
11
Q
Causes of UGI Bleed
A
Varices GI ulcer (? Perforation) Gastritis Mallory Weiss tear Cancer
12
Q
Emergency management of varies
A
A-E Bloods (UE, LFT, FBC, coag, INR, G&S, xmatch, IV site for transfusion Scope and ligate Terlipressin IV ABx
13
Q
Inherited causes of haemolysis
A
Hereditary spherocytosis Hereditary elliptocytosis Thalasaemia SCA G6PD deficiency
14
Q
Management AIHA
A
? Keep warm if cold type (less common) Steroid Rituximab Transfuse Splenectomy
15
Q
Auer rods and myeloblasts
A
AML
