vascular Flashcards
most common cause of PVD
atherosclerosis
Primary risk factors for MI, stroke, chronic mesenteric ischemia, renovascular HTN, and extremist aneurysm:
PVD
end organ involvement PVD
diminished pulses, s4 gallop, residual defect from previous stroke
CV decompensation of PVD
murmur
JVD
third heart sound
rales
SOB
peripheral edema
Baseline lab studies for vascular surgeries
CBC
coags
BMP
biomarkers
12 lead
echo
preop pharm management of patients high risk for MI
Beta Blocker 50-60
Statins
Aspirin
Carotid Endarterectomy indication
TIA w/ >70% stenosis
severe ipsilateral stenosis in pt w stroke
30-70% occlusion w/ ipsilateral symptoms
Asymptomatic are stented
periop MI rate for CEA
2-5%
where is the most common site of CEA?
Bifurcation of the carotid artery & PROXIML internal carotid involvement
Anatomix structures near CEA?
RLN & VAGUS
GLOSSOPHARYNGEAL
HYPOGLOSSAL
MANDIBULAR / FACIAL
Chronic HTN shift cerebral autoregulatory curve to thew
Right
The right shift in autoregulatory curve –> Higher than normal MAP required & causes CBF to become
BP dependent (about 20%)
Cerebral steal occurs (cerebral vascular dilation) with
Hypercarbia –> decreased CBF and increased regional ischemia
Cerebral vasoconstriction occurs with
Hypocarbia –> decreased CBF
inhalation effect on CBF
increased
anesthetic agents on CMRO2
decrease (except ketamine)
Normal Cerebral Blood Flow
50ml/100g/min
20ml of oxygen per 100 ml blood
CMRO2
3-5ml/100g/min
CPP =
MAP - ICP
most common perioperative complication of CEA?
MI
How to protect the brain during CEA?
normocarbia (PaCO2 35-44) (EtCO2 gradient (lower) >5mm)
left shift in the oxyhemoglobin curve
extreme hypocarbia
what is abolished in the area surrounding an acute cerebral infarction due to loss of BV reactivity d/t acid products?
autoregulation
Refers to a condition in which there is an increased blood flow to a particular region of tissue, often after an initial period of reduced blood supply (ischemia).
luxury perfusion
Occurs when blood flow is diverted away from a particular region of the body due to changes in the circulatory system. This often happens when there is a blockage in a major artery, and as a result, blood is “stolen” from one area to supply another region with higher demands. This can occur in the brain, heart, or other organs and may result in ischemia (reduced blood flow) in the area that is deprived of blood
Steal phenomenon (or vascular steal)
(hypercapnia)