Varicella Flashcards
Incubation period
10-21 days
Usually 14-17 days
When is it infectious?
48 hours before the onset of vesicular rash
During the period of vesicle formation
Until all the vesicles are crushed
Most common infectious complication?
Secondary bacterial superinfection of the skin
Most common extracutaneous site of involvement in children?
Cns
Most serious complication following chicken pox?
Varicella pneumonia
What is perinatal varicella?
Maternal disease develops within 5 days before delivery or within 48 hours thereafter
Congenital varicella
Limb hypoplasia
Cicatricial skin lesions
Microcephaly
Zoster opthalmicus
Opthalmic branch of the trigeminal nerve
Serologic evidence of herpes zoster in the absence of skin lesions
Zoster sine herpetica
Ramsay hunt syndrome
Geniculate gangliion of the sensory branch of facial nerve
Most debilitating complication of herpes zoster
Pain
Acyclovir how to give
Famciclovir
Valacyclovir
Given for how many days?
Effective if?
800mg 5x a day
250mg 3x a day
1g 3x a day
5-7 days
Less than 24 hours duration
If herpes zoster
Acyclovir how long?
If immunocompromised?
7-10 days
10mg/kg every 8 hours for 7 days IV acyclovir
Live attenuated vaccine given
<12 yo
> 13 yo
> 50yo
First at 12-15’os then at 4-6 yo
2 doses one month apart
Zostaxax
Vzv ig effective when?
Within 96 hours (preferable within 72 hours) of the exposure
