VAP Flashcards

1
Q

What percentage of patients are affected by VAP? (reference)

A

8-28% (Chastre, 2002)

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2
Q

Define VAP with reference

A

A nosocomial pneumonia in a patient on mechanical ventilation for 48 hours or more (NICE, 2007)

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3
Q

Name 3 requirements for the diagnosis of VAP (reference)

A

fever, leukocytosis, purulent secretions, infiltrate on chest radiography (Niederman, 2005)

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4
Q

How does VAP occur? (reference)

A

after colonisation of the lower airways by pathogens in an immuno-compromised host (Swann, 2008)

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5
Q

How is it distinguished from other pneumonias?

A
diff types micro-organisms are responsible
anti-biotics used to treat
methods of diagnosis
ultimate prognosis
effective preventative measures
Has preventative measures
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6
Q

what percentage of all ICU infections does VAP account for?

What percentage of prescribed anti-biotics are for VAP alone? (Reference)

A

25%

50% (Craven ,2006)

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7
Q

Why does VAP occur? (Factors that increase patient susceptibility)
Include reference

A

Aspiration
ET tubes bypass upper resp. tract defences (you can’t cough/swallow properly)
Duration of intubation
Altered neuro status
Use of histamine 2 blockers/PPI (raise gastric pH)
Altered oral hygeine
Gastric status - sluggish gastric emptying, oesophageal reflux etc
Use of supine/semi recumbent position
Pre-existing lung disease
Immune suppression from disease or medication (impaired innate immunity)
Advanced age
Malnutrition
(Torpy 2007)

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8
Q

Name some management strategies (reference)

Remember prevention is better than cure!!

A

Hand decontamination and PPE; Oral/nasal hygeine; decontamination of GI tract; nutritional support; avoid gastric overdistention; changing vent tubing; humidification; kinetic therapy

(Ruffell & Adamcova 2008)

See online content for more innit!

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9
Q

Name the 2 NICE/NPSA (2008) evidence based recommendations

A

body positioning
Oral antiseptics

See NICE/NPSA pdf.

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10
Q

Why implement, who recommends and what consitutes a Ventilator Care Bundle?

A

Reduces risk of VAP, mortality, length of stay, improves quality of life

DoH ‘High impact interventions’ (2007)

Group of evidence based practise interventions that when grouped together improve patient care - List our VAP care bundle

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11
Q

Name some of the potential elements of a Ventilator Care Bundle

A
Elevation of head 30-45
Sedation hold
Early extubation
DVT prophylaxis
GIT prophylaxis
Humidification
Tubing management
Heated vs non-heated circuits
Suctioning
Routine oral hygeine
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12
Q

Ventilator Care Bundle:

Tight Blood Glucose Control

A

Answer to follow- need to sign up to website to download article

Read Nice sugar guidelines for reasons why we shouldn’t care about tight sugar control

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13
Q

Sedation Hold - name pros and cons (reference)

A

optimize sedation levels and assessment of readiness to extubate
Reduced duration of ventilation (Kress et al,2000)

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14
Q

Head Elevation

A

Two studies 1st 1999 showed reduction in VAP when at 45 degree
2nd 2006 showed no difference

Read around why is would make any difference/ask at work

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15
Q

Why give DVT prophylaxis to DCC patients/ include it on the VAP care bundle?

A

During sepsis relationship between anticoagulant and pro coagulant mechanisms are altered. Damage to endothelial (cells that line blood vessels) impairs activation of protein c - shifting balance to thrombosis.

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16
Q

Why is nutrition/ gut protection so important for DCC patients?

A

To maintain gut structure and function. Aid energy uptake. Supports immune system.

17
Q

Cuff pressure

Cuff technology

A

adequate inflation required to prevent secretions leaking down and allows positive pressure ventilation without air leakage.
Do not over inflate to avoid trachea ischemia,ulceration,necrosis

Read about cuff technology online

18
Q

Early Extubation

A

Interlinked with Sedation hold ensure optimal timing of extubation

Biofilm formation after 12 hours

Silver lining in ETT to reduce VAP being researched

19
Q

Ventilator tubing management

A

Minimise disconnection to prevent contamination

Rectal-pulmonary route of colonisation is a pathway (don’t touch tubes with poo hands)

20
Q

Heat and moisture exchange VS heated circuits

A

No statistical difference in VAP rates found (only small trials conducted)

21
Q

Mouth care / oral hygiene

A

Regular use of toothbrush and tooth paste
Oral antiseptic = chlorhex 2%
Clear oral cavity of secretions regularly

Decontamination associated with lower risk of VAP but not reduction in mortality or ICU stay.

22
Q

Decontamination of digestive tract

A

Again research shows no real difference in VAP rates

23
Q

Enteral feeding control of regurgitation

A

Regular NG aspirations to ensure gastric emptying, particularly before lowering head.

Aspiration pneumonia decreases reducing patient ICU stay

24
Q

Kinetic beds

A

Reduces VAP but not mortality rates, length of stay or time on vent

Poorly tolerated by conscience patient

Expensive

See CXR online for evidence of goodness!