Valvular Heart Disease - Johnston Flashcards
Stenosis leads to ____
Hypertrophy
Regurg/Insufficiency leads to ____
Dilation
Mitral Stenosis
Rheumatic heart disease
Major Jones Criteria for RHD
- Carditis (myo, peri)
- Migratory polyarthritis
- SubQ nodules
- Sydenham’s chorea
- Erythema marginatum
Jones minor criteria for RHD
- Fever
- Arthralgia
- Increased sed rate or CRP
- Leukocytosis
- Prolonged PR interval
- Elevated ASO or anti-DNase B
How to Dx RHD
2 major
1 major and 2 minor
Pathophysiology of aortic stenosis (results of it)
- LV pressure –> LVH –> diastolic LV dysfunction –> syncope, HF
- Reduced coronary flow –> angina
Symptoms of aortic stenosis
- Angina
- Syncope
- Exertional dyspnea
- Heart failure
Exam findings for aortic stenosis
- Systolic ejection murmur radiating to suprasternal notch and carotids (2nd ICS RSB)
- Narrow pulse pressure
- Delayed pulses (carotid, peripheral)
ECG - aortic stenosis
- Left atrial enlargement
- LVH (w/ strain)
Pharma therapy for aortic stenosis
Avoid what?
- Digitalis, diuretics, nitroglycerin
- Avoid vasodilators (increased pre-load)
Surgical treatment for AS
- Percutaneous balloon valvuloplasty, temporary valve replacement
Causes of aortic regurgitation (7)
- HTN (increased aortic pressure)
- Endocarditis
- Marfan’s (aortic root dilation)
- Ankylosing spondylitis
- Aortic dissection
- Syphilis (aortic root dilation)
- Collagen vascular disease
Pathophysiology (results) of ACUTE aortic regurgitation
High diastolic LV pressure –> premature mitral closure –> LV ischemia and failure
Pathophysiology (results) of CHRONIC aortic regurgitation
Decreased SV over time –> hyperdynamic (overloaded) circulation –> systolic HTN –> pressure/volume overload –> concentric LVH