Valvular heart disease Flashcards

1
Q

What causes the first heart sound (S1)?

A

The closing of the atrioventricular valves (mitral and tricuspid) at the start of systole.

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2
Q

What causes the second heart sound (S2)?

A

The closing of the semilunar valves (aortic and pulmonary) at the end of systole.

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3
Q

What is a third heart sound (S3) and when is it heard?

A

S3 is caused by rapid ventricular filling and is heard around 0.1 seconds after S2. It can be normal in young people but may indicate heart failure in older adults.

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4
Q

What is a fourth heart sound (S4) and when is it heard?

A

S4 is heard before S1 and indicates a stiff or hypertrophic ventricle, often caused by turbulent flow from the atria contracting against a non-compliant ventricle.

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5
Q

How do you best listen for low-pitched sounds (e.g., murmurs)?

A

Use the bell of the stethoscope.

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6
Q

Where do you auscultate for heart murmurs?

A

Pulmonary area: 2nd intercostal space, left sternal border.
Aortic area: 2nd intercostal space, right sternal border.
Tricuspid area: 5th intercostal space, left sternal border.
Mitral area: 5th intercostal space, mid-clavicular line (apex area).

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7
Q

What mnemonic is used to assess heart murmurs?

A

‘SCRIPT’

S: Site
C: Character
R: Radiation
I: Intensity
P: Pitch
T: Timing

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8
Q

What does a Grade I murmur mean?

A

A Grade I murmur is difficult to hear.

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9
Q

What is the murmur grading scale?

A

Grade I: Difficult to hear.
Grade II: Quiet.
Grade III: Easy to hear.
Grade IV: Easy to hear with a palpable thrill.
Grade V: Audible with stethoscope barely touching the chest.
Grade VI: Audible with stethoscope off the chest.

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10
Q

What does aortic stenosis cause in terms of heart sounds?

A

Aortic stenosis causes a high-pitched, ejection-systolic murmur with a crescendo-decrescendo character and radiates to the carotids.

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11
Q

What are common signs of aortic stenosis?

A

Thrill in the aortic area.
Slow rising pulse.
Narrow pulse pressure.
Exertional syncope.

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12
Q

What are common causes of aortic stenosis?

A

Idiopathic age-related calcification.
Bicuspid aortic valve.
Rheumatic heart disease.

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13
Q

What murmur is heard in aortic regurgitation?

A

Aortic regurgitation causes an early diastolic, soft murmur, and may have an Austin-Flint murmur (rumbling at the apex).

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14
Q

What are common signs of aortic regurgitation?

A

Collapsing pulse.
Wide pulse pressure.
Heart failure and pulmonary oedema.

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15
Q

What causes mitral stenosis?

A

Mitral stenosis is most commonly caused by rheumatic heart disease or infective endocarditis.

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16
Q

What is a classic murmur for mitral stenosis?

A

A low-pitched, mid-diastolic rumbling murmur with a loud S1 and an opening snap after S2.

17
Q

What are signs of mitral stenosis?

A

Tapping apex beat.
Malar flush.
Atrial fibrillation.

18
Q

What is heard in mitral regurgitation?

A

A pan-systolic, high-pitched ‘whistling’ murmur that radiates to the left axilla.

19
Q

What are the causes of mitral regurgitation?

A

Idiopathic weakening of the valve.
Ischaemic heart disease.
Infective endocarditis.
Rheumatic heart disease.
Connective tissue disorders (e.g., Ehlers-Danlos, Marfan syndrome).

20
Q

What is the murmur heard in tricuspid regurgitation?

A

A pan-systolic murmur.

21
Q

What are signs of tricuspid regurgitation?

A

Raised JVP with giant C-V waves.
Pulsatile liver.
Peripheral oedema.
Ascites.

22
Q

What causes pulmonary stenosis?

A

Pulmonary stenosis is usually congenital and associated with conditions like Noonan syndrome or Tetralogy of Fallot.

23
Q

What is the murmur heard in pulmonary stenosis?

A

An ejection systolic murmur, loudest in the pulmonary area, with deep inspiration. There is a widely split second heart sound.

24
Q

What is a common cause of pulmonary stenosis?

A

Pulmonary stenosis is commonly congenital, such as in Noonan syndrome and Tetralogy of Fallot.