Prosthetic valves Flashcards

1
Q

What is the most common indication for valve replacement surgery?

A

Aortic stenosis is the most common indication for valve replacement surgery.

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2
Q

What is the second most common indication for valve replacement surgery?

A

Mitral regurgitation is the second most common indication for valve replacement surgery.

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3
Q

What is the most common surgical approach for valve replacement?

A

The most common surgical approach is a midline sternotomy (a vertical incision down the middle of the chest).

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4
Q

What is the alternative surgical approach for minimally invasive mitral valve surgery?

A

A right-sided mini-thoracotomy incision may be used for minimally invasive mitral valve surgery.

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5
Q

What is the lifespan of a bioprosthetic valve?

A

A bioprosthetic valve has a limited lifespan of around 10 years.

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6
Q

What is the primary difference between bioprosthetic and mechanical valves?

A

Bioprosthetic valves last about 10 years, while mechanical valves last over 20 years but require lifelong anticoagulation therapy.

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7
Q

What type of anticoagulation is required for patients with mechanical valves?

A

Patients with mechanical valves require lifelong anticoagulation with warfarin, aiming for an INR target range of 2.5 – 3.5.

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8
Q

What is the risk for thrombus formation in mechanical heart valves?

A

Mechanical heart valves carry a risk of thrombus formation due to blood stagnation and clotting.

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9
Q

Which valve is commonly used and has the smallest risk of thrombus formation?

A

The St. Jude bileaflet valve, which features two tilting metal discs, has the smallest risk of thrombus formation.

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10
Q

What sound can be heard during auscultation of a mechanical heart valve?

A

A click sound may replace S1 or S2: Mitral valve: Click replaces S1. Aortic valve: Click replaces S2.

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11
Q

What are the major complications of mechanical heart valves?

A

The three major complications are:
* Thrombus formation (blood clots).
* Infective endocarditis (infection in the valve).
* Hemolysis (anemia caused by blood damage in the valve).

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12
Q

What is TAVI and when is it used?

A

TAVI (Transcatheter Aortic Valve Implantation) is used for patients with severe aortic stenosis who are high-risk for open surgery. It involves inserting a catheter through the femoral artery to implant a bioprosthetic valve.

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13
Q

Do patients who undergo TAVI require anticoagulation therapy?

A

No, patients with a TAVI do not typically require warfarin because the valve is bioprosthetic.

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14
Q

What is the rate of infective endocarditis in patients undergoing valve replacement surgery?

A

Infective endocarditis occurs in about 2.5% of patients undergoing surgical valve replacement, and slightly lower in TAVI patients (1.5%).

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15
Q

What are the common causes of infective endocarditis in prosthetic valves?

A

It is usually caused by gram-positive cocci organisms:
* Staphylococcus
* Streptococcus
* Enterococcus

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