Valvular Heart Disease Flashcards
What is valvular heart disease?
It refers to a group of conditions in which the heart valves have become damaged or diseased
What are the four valvular heart diseases?
Mitral stenosis
Mitral regurgitation
Aortic stenosis
Aortic regurgitation
What is the function of heart valves?
They are structures which ensure blood flows in only one direction
What are the two classifications of heart valves?
Atrioventricular Valves
Semilunar Valves
How do we remember the location of the heart valves?
From right to left
All (Aortic)
Prostitutes (Pulmonary)
Take (Tricuspid)
Money (Mitral)
What are atrioventricular valves?
They are located between the atria and corresponding ventricle
What are the two atrioventricular valves?
Tricuspid Valve
Mitral Valve
Where is the tricuspid valve located?
It is located between the right atrium and the right ventricle at the right atrioventricular orifice
What is another term for the mitral valve?
Bicuspid valve
Where is the mitral valve located?
It is located between the left atrium and the left ventricle at the left atrioventricular orifice
What are the semilunar valves?
They are located between the ventricles and their corresponding artery
What are the two semilunar valves?
Pulmonary valve
Aortic valve
Where is the pulmonary valve located?
It is located between the right ventricle and the pulmonary trunk at the pulmonary orifice
Where is the aortic valve located?
It is located between the left ventricle and the ascending aorta at the aortic orifice
What are the heart sounds caused by?
They are generated by the beating heart and the resultant flow of blood through it
What is the first heart sound (S1) caused by?
It is caused by the closing of the atrioventricular valves at the start of systolic contraction of the ventricles
What is the second heart sound (S2) caused by?
It is caused by the closing of the semilunar vales once the systolic contraction is complete
What is the third heart (S3) sound caused by?
It is when rapid ventricular filling causes the chordae tendinae to pull to their full length
When is S3 heard?
> 0.1s after S2
In which individuals does S3 suggest pathology? What pathology does it suggest? Why?
Older patients
Heart failure
The ventricles and chordae are stiff and weak so they reach their limit much faster than normal
What is the fourth heart (S4) sound caused by?
It is caused by turbulent blood flow from an atria contracting against a non-compliant ventricle
When is S4 heard?
Directly before S1
What does S4 indicate?
Stiff ventricle
Hypertrophic ventricle
What is mitral stenosis?
It is a condition in which there is narrowing of the mitral valve. This results in an obstruction of blood flow from the left atrium to the left ventricle
In which three locations, does mitral stenosis result in an increased pressure?
Left atrium
Pulmonary vasculature
Right side of the heart
What is the overall result of mitral stenosis?
Left atrial hypertrophy
What are the four causes of mitral stenosis?
Rheumatic fever
Infective endocarditis
Mucopolysaccharidoses
Carcinoid endocardial fibroelastosis
What is the most common cause of mitral stenosis?
Rheumatic fever
What are the five clinical features of mitral stenosis?
Dyspnoea on exertion
Haemoptysis
Chest pain
Malar flush
Atrial fibrillation
What are the five mitral stenosis murmur features?
Mid-Diastolic, Low Pitched, Rumbling Murmur
Louder Murmur on Expiration
Loud S1
Tapping Apex Beat
Low Volume Pulse
What three investigations can be used to diagnose mitral stenosis?
ECG
CXR
ECHO
What three features indicate mitral stenosis on ECG?
Atrial Fibrillation
Broad P wave > 0.12 seconds
P Mitrale
What two features indicate mitral stenosis on CXR?
Left Atrial Enlargement
Pulmonary Oedema
What three features indicate mitral stenosis on ECHO?
Mitral Valve Cross-Section < 1sqcm
Thickening & Scarring of Valve Cusps
Commissure Fusion
What is the normal cross-sectional area of the mitral valve?
4-6 sq cm
When is conservative management of mitral stenosis recommended?
It is recommended in individuals who are asymptomatic
What are the two conservative management options for mitral stenosis?
We manage cardiovascular risk factors
We regularly monitor with ECHO scans
When is pharmacological management of mitral stenosis recommended?
It is recommended as a first line treatment option in individuals who are symptomatic
What are the two pharmacological treatment options for mitral stenosis?
Diuretics
Anticoagulants
How are diuretics used to manage mitral stenosis?
They reduce the fluid build-up in the lungs and heart.
When are anticoagulants administered to treat mitral stenosis?
They administered to individuals who develop atrial fibrillation as a result of their mitral stenosis
When is surgical management of mitral stenosis recommended?
It is recommended as a second line treatment option in individuals who are symptomatic
What three surgeries are used to treat mitral stenosis?
Percutaneous Balloon Mitral Valvuloplasty
Commissurotomy
Mitral valve replacement
What is percutaneous balloon mitral valvuloplasty?
It is a procedure in which a catheter, with an attached balloon, is inserted into an artery and guided towards the narrowed valve
Once in position, the balloon is inflated to widen the valve – improving blood flow
The balloon is then deflated, and the catheter with the balloon is removed
What is commissurotomy ?
It is a procedure in which calcium deposits and scar tissue are removed to clear the valve passageway