Pericarditis Flashcards

1
Q

What is pericarditis?

A

It is defined as a condition in which there is inflammation of the pericardium, the fibrous sac which surrounds the heart

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2
Q

What are the nine risk factors associated with pericarditis?

A

Male Gender

Middle Aged 40 – 60 Years Old

Bacterial/Viral/Fungal Infection

Connective Tissue Disorders

Hypothyroidism

Post Myocardial Infarction

Uraemia

Malignancy

Drug Administration

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3
Q

What is the most common risk factor associated with pericarditis?

A

Bacterial/Viral/Fungal Infection

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4
Q

Which bacterial infection is associated with pericarditis?

A

Staphylococcus tuberculosis

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5
Q

What viral infection is associated with pericarditis?

A

Coxsackievirus

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6
Q

Which fungal infection is associated with pericarditis?

A

Histoplasmosis

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7
Q

What two connective tissue disorders are associated with pericarditis?

A

Rheumatoid arthritis

Systemic lupus erythematosus

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8
Q

Which two malignancies are associated with pericarditis?

A

Lung cancer

Breast cancer

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9
Q

Which drug is associated with pericarditis?

A

Hydralazine

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10
Q

What are the eight clinical features of pericarditis?

A

Pleuritic Chest Pain

Dry Cough

Dyspnoea

Pericardial Rub

Pericardial Effusion Features

Cardiac Tamponade Features

Tachycardia

Tachypnoea

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11
Q

What is pleuritic chest pain?

A

It is pain which is exacerbated by deep inspiration and when lying down

However, it is relieved by sitting forwards

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12
Q

What are the two other features of the chest pain associated with pericarditis?

A

Retrosternal

The pain radiates to the neck, shoulder, arms and trapezius

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13
Q

How do we assess for a pericardial rub?

A

It is loudest at the left lower sternal border

It is easiest to hear when the patient leans forward

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14
Q

What are the three features of a pericardial effusion?

A

Soft heart sounds

Tubular breath sounds in the left axilla/lung base

Obscured apex beat

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15
Q

What are the three features of cardiac tamponade?

A

Hypotension

Muffled heart sounds

Raised JVP

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16
Q

What three investigations are used to diagnose pericarditis?

A

Blood Tests

ECG Scan

ECHO Scan

17
Q

How are blood test results used to diagnose pericarditis?

A

There is no single diagnostic laboratory test for pericarditis

However, blood tests can be used to exclude other causes or indicate the underlying aetiology

18
Q

What four blood test results indicate pericarditis?

A

Increased WCC Levels

Increased CRP Levels

Increased ESR Levels

Increased Troponin Levels

19
Q

What does an elevated troponin level in pericarditis indicate?

A

Myopericarditis

20
Q

What is the gold standard investigation used to diagnose pericarditis?

21
Q

What are the three features of pericarditis on ECG scans?

A

Global Saddle-Shaped ST Elevation

Global PR Depression

Low Voltage QRS Complexes

22
Q

How are ECHO scans used to diagnose pericarditis?

A

They should be conducted in all patients with suspected pericarditis, in order to assess for development of pericardial effusion

23
Q

What type of ECHO scan is preferred to investigate pericarditis - transoesophageal or transthoracic?

A

Transthoracic

24
Q

Where can pericarditis patients usually be managed?

25
What two features would indicate admission of pericarditis patients?
Fever > 38°C Elevated troponin
26
What are the two conservative management options of pericarditis?
Treat Underlying Aetiology Physical Activity Restriction
27
What are the three pharmacological management options of pericarditis?
Non-Steroidal Anti-Inflammatories Colchicine Corticosteroids
28
When are NSAIDs used to manage pericarditis?
They are the first line pharmacological management option
29
Name three NSAIDs used to manage pericarditis
Ibuprofen Aspirin Naproxen
30
What is the mechanism of action of colchicine?
Anti-inflammatory
31
When is colchicine used to manage pericarditis?
They are the first line pharmacological management option when administered in combination with NSAIDs
32
When are corticosteroids used to manage pericarditis?
They are the second line pharmacological management option
33
What are the four complications of pericarditis?
Chronic Pericarditis Constrictive Pericarditis Pericardial Effusion Cardiac Tamponade