Valvular disorders Flashcards
Infective endocarditis
Can cause damage to valves
Subacute: In those w/ preexisting valve disease
-req months of treatment
Acute: In those w/ healthy valves
-Rapidly progressive disease
Caused by IVDA (IV drug abuse)
Risk factors for infective endocarditis
Aging IVDA Prosthetic valve Dialysis Hospital IV devices carrying healthcare assoc. infection
IE manifestations
Low CO Organ damage from emboli Heart murmur Fever!!!! Arthralgia/myalgia Clubbing of fingers
Splinter hemorrhages (black streaks in nail bed)
Osler’s nodes (painful red/purp pea sized lesions)
Janeway’s lesions (flat, painless small red spots)
systolic murmur
Diagnostics for IE (assessing)
Dental, surgical, gynecological procedures in past 3-6 months
blood drawn from 3 different sites in an hour
Guidelines for dx of IE
2 major + 1 minor
1 major + 3 minor
5 minor
Major:
- Pos blood cultures (MOST IMPORTANT)
- Microorganisms consistent w/ IE from 2 separate cultures
- Endocardial involvement
- New valvular vegetation
Minor:
- Predisposing heart condition or IV drug use
- Vascular phenomena
- Immunologic phenomena
- Microbiologic evidence
- Echocardiograph findings consistent w/ IE but not meeting major criteria
Chest x ray can show Cardiomegaly
ECG: 1st or 2nd AV block
Vegetations forming from IE
Primary lesion of IE
Can embolize
Risk INCREASES once treatment starts
L heart: embolize to all organs
R heart: embolize to lungs
Target organ damage from IE
Spleen: Sharp LUQ pain, rigid
Kidney: Low urinary output, flank pain, hematuria, azotemia (nitrogen in blood)
Arms/legs: gangrene
Brain: Hemiplegia, ataxia, aphasia, LOC change
Pulmonary embolism
Most important IE diagnosing factor
POSITIVE BLOOD CULTURE
- report to provider
IE collab care
Prophylaxis:
-antibiotics
Amoxicillin 3g po 1h prior
If allergic to penicillin: Clindamycin 600mg po 1h prior
High risk: Amoxicillin 1g IV, gentamycin 120mg IV at induction. Amoxicillin .5g PO 6hr after
IE drug therapy
MUST identify causative organism first!!!
Long term treatment: IV antibiotics in hospital and after discharge
Monitor w/ more blood cultures
Monitor antibiotic levels for therapeutic range
Fungal/prosthetic valve endocarditis responds poorly to treatment- expect valve replacement and long term antibiotics
Long term implementation
Long term antibiotics on PICC
If shows S&S of HF go back to inpatient
Teach S&S of infection, HF, emboli (confusion, decreased CO, skin discoloration)
Eval: Normal temp Tolerating ADLs Urinary output 30+mL/hr Demonstrate understanding
Pericarditis
Acute (rapid)
Subacute (weeks-months after an event)
Chronic (6+months)
causes:
Often idiopathic
Infectious: Viral, bacterial, fungal, LYME
Non-infectious: Acute MI, Ca, renal failure, trauma
Autoimmune: Dressler syndrome (post MI syndrome), drug reactions, Rheumatic disease
Acute pericarditis manifestation triad
Pain: Progressive, severe, sharp -Inc. with inspiration and when supine May radiate to neck, arm, L shoulder -Dyspnea: deep breathing hurts-->lot of small breaths--> tachypnea
Friction Rub: HALLMARK SIGN
- Scratching, grating, high pitched
Heart rubbing on viscera–> inflamed!
Heard best at L sternal border w/ pt lean forward
ECG changes:
ST elevation
Acute pericarditis pain symptoms
Pain: Progressive, severe, sharp -Inc. with inspiration and when supine May radiate to neck, arm, L shoulder -Dyspnea: deep breathing hurts-->lot of small breaths--> tachypnea
Acute pericarditis Friction Rub symptoms
Friction Rub: HALLMARK SIGN
- Scratching, grating, high pitched
Heart rubbing on viscera–> inflamed!
Heard best at L sternal border w/ pt lean forward