Valvular and Ischemic Heart Disease - Therapy Flashcards
What are some causes of cardiac ischaemia?
Atherosclerosis
Embolism
Coronary thrombosis
Airtuc dussection
Arteritides
Congenital
What is aortic dissection?
Tear in the wall of the aorta
What is a tear in the wall of the aorta called?
Aortic dissection
What are some manifestations of ischaemic heart disease?
Angina
Myocardial infarction
Arrythmias
Chronic heart failure
Death
What is arrythmias?
Irregular heart beat
What is irregular heart beat called?
Arrythmias
What are indications for coronary artery bypass grafting (CABG)?
Symptomatic
Prognostic
What does CABG stand for?
Coronary artery bypass grafting
What is coronary artery bypass grafting (CABG)?
Surgical procedure used to treat coronary heart disease by diverting blood around a narrowed or clogged part of arteries to improve blood flow to the heart
What is a surgical procedure used to treat coronary heart disease by diverting blood around a narrowed or clogged part of arteries to improve blood flow to the heart called?
Coronary artery bypass grafting (CABG)
What is used for the seleciton of patients for CABG?
Adequate lung function
Adequate mental function
Adequate hepatic function
Descending aorta okay
Distal coronary targets okay
Left ventricle ejection fraction (LV EF) > 20%
What does LV EF stand for?
Left ventricle ejection fraction
What are contraindications for CABG?
Reversed suphenous vein
Internal mammary arteries
Radial arteries
What is sternotomy?
Surgical procedure in which a verticle incision is made along the sternum, after the sternum itself is divided
What is the surgical procedure in which a verticle incision is made along the sternum, after the sternum itself is divided called?
Sternotomy
What are sternotomy related problems?
Wire infections
Painful wires
Sternal dehiscence
Sternal malunion
What is sternal dehiscence?
Process of seperation of the body sternum
What is the process of seperation of the body sternum called?
Sternal dehiscence
What is sternal malunion?
Sternal pain with clicking and/or instability for more than 6 months in the absence of infection
What is sternal pain with clicking and/or instability for more than 6 months in the absence of infection called?
Sternal malunion
What are some possible post-operative problems in cardiac surgery?
Cardiac tamponade
Death
Stroke
What is cardiac tamponade?
Clinical syndrome caused by the accumulation of fluid in the pericardial space resulting in reduced ventricular filling
What is a clinical syndrome caused by the accumulation of fluid in the pericardial space resulting in reduced ventricular filling?
Cardiac tamponade
What are the primary features of cardiac tamponade?
Raised central venous pressure
Raised heart rate
Low blood pressure
What are the secondary features of cardiac tamponade?
Oliguria
Increased oxygen requirements
Metabolic acidosis
What is oliguria?
Urine output less than:
1mL/kg/hr in infants
0.5mL/kg/hr in children
400 or 500ml/24 hours in adults
What is the treatment of tamponade?
Chest re-opening
What are the long term outcomes post CABG?
50% have no further cardiac problems 10 years later
5% may require a repeat CABG
What is the most common valve surgery in adults?
Mitral and aortic
What is the most common valve surgery in children?
All 4
What are some causes of valvular heart disease in adults?
Degenerative
Congenital
Infective
Inflammatory
Left ventricle or right ventricle dilation
Trauma
Neoplastic
Paraneoplastic
What are 3 common valve problems requiring surgery?
Senile tricuspid aortic stenosis
Bicuspid aortic stenosis
Degenerative mitral regurgitation
What is rheumatic fever related to?
Steptococcal infection
What does rheumatic fever lead to?
Pancarditis
What is the treatment of rheumatic fever?
Aspirin and bed rest
What is the most common heart problem worldwide?
Rheumatic heart disease
What is endocarditis?
Infection of the endocardium
What is infection of the endocardium called?
Endocarditis
What are the 2 most common organisms to cause endocarditis?
1) Strep virdans
2) Staph aureus
What gives rise to subacute bacterial endocarditis?
Strep virdans
What gives rise to acute bacterial endocarditis?
Staph aureus
Is the chances of curing endocarditis higher with antibiotics when it is caused by strep virdans or staph aureus?
Strep virdans
What are indications for surgery in endocarditis?
Severe vavular regurgitation
Large vegetations
Persistance pyrexia
Progressive renal failure
What is to be given after surgery for endocarditis?
Antibiotics by IV for 6 weeks post-operatively
What is aortic stenosis?
Narrowing of the aortic valve opening
What does aortic stenosis typically present in?
Heart failure
Angina
Syncope epidoses
Asymptomatic incidental finding
What is the murmur like in aortic stenosis?
Easily heard
What investigations are done for aortic stenosis?
ECG
ECHO
What treatment is done for severe aortic stenosis?
Aortic valve replacement
What is aortic regurgitation?
Leaky aortic valve causing backflow of blood
What does aortic regurgiation present as?
Heart failure
Angina
Asymptomatic incidental finding
What is the murmur due to aortic regurgitation like?
Hard to hear
What is the relationship between the severity of aortic regurgitation and the loudness of the murmur?
The louder the mumur the more severe the aortic regurgitation
What is the treatment for severe aortic valve regurgitation?
Aortic valve replacement
What is mitral stenosis?
Narrowing of the mitral valve
What is the murmur due to mitral stenosis like?
Hard to hear
What may the patient have to do to hear the murmur due to mitral steonsis?
Exercise
When is surgery used to treat mitral stenosis?
When mitral valve area is less than 1.5cm2 on ECHO
What is mitral regurgitation?
Leaking of the mitral valve causing backflow of blood
What is severe mitral regurgitation associated with?
Left ventricular and left atrial dilation
Onset of atrial fibrillation
Pulmonary hypertension
What is the treatment for severe mitral regurgitation?
Mitral valve replacement
What is severe mitral regurgitation on ECHO characterised by?
Blood flow reversal in pulmonary veins
What is a cardiopulmonary bypass?
Technique in which a machine takes over the function of the heart and lungs during surgery
What is a technique in which a machine takes over the function of the heart and lungs during surgery?
Cardiopulmonary bypass
What happens during a caridopulmonary bypass?
Blood drained from right atrium and returned to the ascending aorta
What is the maximum time of cardiopulmonary bypass?
12 hours
What is a common problem with cardiopulmonary bypass?
Coagulopathy
What are different choices of heart valve replacements?
Biological valve
Mechanical valve
What is the advantage and disadvantage of a biological valve replacement?
No warfarin required but the valve wears out after 15 years
What is the advantage and disadvantage of mechanical valve replacement?
Warfarin required for life but valve lasts for more than 40 years
When is repair of the valve better than replacement?
For the mitral valve