Valve Replacement Flashcards
What are the examination findings/signs of mechanical valve replacement?
- Midline sternotomy scar in all valve replacement
- Look for concomittant CABG harvest scars
- Look for left lateral thoracotomy scar - previous mitral valvotomy
- Complex scars -> Tetralogy of Fallot - Apex beat - deviated vs not deviated
- Metallic and distinct heart sound: S1 or S2
- Ball and cage: whoosing sound and double metallic click (closing > opening)
- Disc: metallic click without murmur
(Careful of double metallic valve replacement - confused with SE valve) - Valve thrombosis or flow murmur?
- All AVR will produce ESM (which may also signify AVR stenosis/thrombosis)
- SE MVR will produce MDM at apex loudest on expiration in left lateral position (which also signify MVR stenosis /thrombosis)
(Always comment in PACES TRO valve thrombosis) - Any untreated murmurs or new onset valve failure
- Loss of crisp click in metallic valve
- New murmurs (regurgitation): PSM for MVR leak; EDM for AVR leak
- Change in character or intensity of existing sound
- Low volume, slow rising pulse - stenotic AVR or normal in Starr-Edwards valve
- Large volume or collapsing pulse - malfunctioning AVR with AR - Signs of overwarfarinisation
- Signs of anaemia - blood loss, haemolysis, endocarditis
- +/- pulmonary hypertension if longstanding prior to surgery (mitral lesion > aortic lesion)
How to determine what was the original vavular lesion prior to valve replacement?
- Which valve is replaced? mitral vs aortic
- S1 metallic -> mitral valve replacement
- S2 metallic -> aortic valve replacement
(S1 is closure of mitral/tricuspid, S2 is closure of aortic/pulmonary)
- Apex beat deviation
- Deviated: MR (S1 metallic) ; AR (S2 metallic)
- Not deviated: MS (S1 metallic) ; mild AS (S2 metallic) - severe AS with LVH will deviate
- Careful about double metallic valve replacement
Clues in the event of double audible click (Starr Edwards) : - Left lateral thoracotomy scar - previous mitral valvotomy -> MVR - Pulmonary hypertension and right heart failure more common in MV disease - Starr Edwards mitral valve - S1 closing click, **S2 native valve + opening click**
How would you investigate valve dysfunction?
- History and examination
- TTE - often difficult
- TEE - MV prosthesis
- Cinefluoroscopy
What are the criterias for valve replacement in aortic regurgitation?
Symptomatic: severe aortic regurgitation with angina or dyspnoea
Asymptomatic: mod/severe aortic regurgitation undergoing other cardiac surgery, left ventricular dysfunction, dilated left ventricle
What are the indications for aortic valve replacement?
- Aortic stenosis
- Severe symptomatic (gradient > 50mmHg)
- Mod-severe asymptomatic: concomittant CABG, LVSD > 40mmHg, abnormal BP response, VT, valve area <0.6cm2 - Aortic regurgitation
- Severe symptomatic: angina, dyspnoea
- Mod-severe asymptomatic: concomittant CABG, EF < 50%, LVESD > 55mm - Infective endocarditis not responding to medical therapy
- Enlarging aortic root diameter irrespective of degree of aortic regurgitation
- Sinus of valsalva aneurysm rupture
- Aortic dissection causing aortic regurgitation
Which patients should receive bioprosthetic valves?
Anticoagulation is contraindicated
Life expectancy shorter than expected life span of the prosthesis
Patient age >70 (degeneration is slower)
What are the complications of prosthetic valves? (Metallic and tissue)
- Thromboembolism (5%)
- < 5mm for IV heparin, > 5mm for fibronolysis or valve replacement - Complications of anticoagulation
- Overanticoagulation -> BGIT, anaemia, ICB - Valve dysfunction
- Leaking, dehiscence, fracture
- Stiffening or calcification and stenosis (bioprosthetic)
- Perforation and regurgitation (bioprosthetic)
(Valve strut failure in Bjork Shiley valve - high mortality) - Infective endocarditis
- Haemolytic anaemia (mechanical valve) and jaundice
- AV conduction defect (in aortic lesion)
What are the advantages and disadvantages of mechanical valves?
Advantages:
- Longer life span of valve compared to biological valve
- Lowere rate of re-operation
Disadvantages:
- Life long anticoagulation (INR 2.5 - 3.5)
What are the indications for mitral valve replacement?
- Mitral stenosis
- Pulmonary congestion and pulmonary hypertension
- Haemoptysis
- Recurrent thromboembolism despite anticoagulation - Mitral regurgitation
- LV dysfunction
- EF < 60% even if asymptomatic
- LVESD > 45mm even if asymptomatic
What are the indications for anticoagulation in mitral valve disease?
Valvular atrial fibrillation (mitral stenosis)
Previous embolic disease
What are the types of mechanical heart valves?
- Ball and cage (Starr Edwards)
- Ball valve hitting cage in systole/diastole with whooshing sound of blood. double metallic click - Single tilting disc (Bjork-Shiley) - low incidence of haemolysis
- Double tilting disc (St Judes)
- Metallic click of valve shutting, no murmur
Which patients should receive mechanical valve?
- Young age - longer lifespan of mechanical valve
(However homografts are still 1st choice of replacement) - Already on long term anticoagulation
What are the types of bioprosthetic heart valves?
What are the advantages and disadvantages?
- Xenograft (porcine or bovine)
- Homograft (cadaveric)
Advantages
- No need lifelong anticoagulation (3 months only) unless AF -> safer in elderly, pregnancy
- Homografts are more resistant to infection (useful in replacing infected valves)
Disadvantages
- Less durable (mitral 7 years, aortic 10 years)
- High rate of re-operation
- Prone to calcification
What are the causes of anaemia in valve replacement?
- Overanticoagulation
- Haemolytic anaemia
- Infective endocarditis
When to suspect clinically that valve has malfunctioned?
- New murmur
- Change in characteristic or intensity of pre-existing murmur/audible sound