Vaccines-in-PHC-final-edit-Asem-Juhani Flashcards

1
Q

What is immunity?

A

Immunity is the body’s ability to recognize and tolerate cells and material that is indigenous to it, and to recognize and eliminate foreign substances.

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2
Q

How does the similarity of a vaccine to the disease-causing organism affect immune response?

A

The more similar a vaccine is to the disease-causing form of the organism, the better the immune response to the vaccine will be.

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3
Q

What factors can affect the immune response to vaccines?

A

Factors include age, genetics, nutrition, maternal antibodies, other current illnesses, nature and dose of antigen, route of administration, and vaccine composition.

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4
Q

When was the first vaccine developed and for what disease?

A

The first vaccine was developed in 1796 by Edward Jenner for smallpox from cowpox lesions.

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5
Q

What significant vaccine development occurred after the Spanish flu pandemic?

A

Influenza vaccine trials were conducted in 1918, and a vaccine was later developed in 1945.

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6
Q

What milestone was achieved in 1980 regarding smallpox?

A

The eradication of smallpox was achieved after intense and coordinated world-wide efforts.

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7
Q

What was the WHO’s Essential Programme on Immunization (EPI) launched for?

A

EPI was launched in 1974 targeting diseases like diphtheria, measles, tetanus, polio, TB, and whooping cough.

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8
Q

What challenges did the US face with whooping cough vaccination?

A

After cases hit an all-time low in 1976, fears about rare side effects outweighed fears of the disease itself.

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9
Q

What impact have EPI vaccines had on global health?

A

EPI vaccines are considered one of the most successful global health interventions and cost-effective ways to save lives.

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10
Q

What was the situation of mumps before vaccines?

A

Mumps was a common cause of aseptic meningitis and hearing loss among children and hospitalization among military personnel.

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11
Q

When was the mumps vaccine introduced?

A

The mumps vaccine was introduced in the 1960s.

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12
Q

What is the status of Jordan’s EPI?

A

Jordan’s EPI, founded in 1979, is effective, resulting in high vaccination coverage against preventable diseases.

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13
Q

What was the vaccination coverage for children aged 12-23 months in Jordan according to the 2023 survey?

A

92% of children aged 12-23 months were fully vaccinated by basic antigens.

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14
Q

What percentage of children aged 12-23 months received the BCG vaccine in Jordan?

A

98% of children in that age group received the BCG vaccine.

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15
Q

What disparities were noted in vaccination coverage in Jordan?

A

Higher rates were observed among children with Jordanian and Syrian mothers compared to those with mothers from other nationalities.

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16
Q

What are some factors affecting vaccine delivery and vaccination programs?

A

Factors include misinformation, poverty, geographical location, education, and unexpected events like pandemics.

17
Q

What was the impact of the COVID-19 pandemic on vaccination programs?

A

Vaccination programs were hindered by lockdowns, fear of infection, and parental refusal for routine vaccinations.

18
Q

What was the outcome of a study on childhood vaccination in the 20th century USA?

A

Diphtheria, Measles, and Polio deaths dropped from thousands in 1900 to 0 in 2015.

19
Q

How many lives are estimated to be saved per year due to vaccines?

A

The original six vaccines, along with hepatitis B and Hib vaccines, are estimated to save between 2-3 million lives per year.

20
Q

What are the three main areas to consider when introducing a new vaccine?

A

The three areas are Vaccine, Disease, and Healthcare System.

21
Q

What does the WHO provide for the introduction of new vaccines?

A

The WHO provides a checklist of 14 main points covering policy, objectives, monitoring, logistics, and waste management.

22
Q

What is the source for the history of vaccination?

A

World Health Organization (WHO) provides a brief history of vaccination.

23
Q

Where can information on mumps be found?

A

The CDC provides detailed information on mumps.

24
Q

What study discusses mass psychogenic illness related to vaccination in Jordan?

A

Kharabsheh et al. published a study on mass psychogenic illness following tetanus-diphtheria toxoid vaccination in Jordan.

Bulletin of the World Health Organization, 2001, 79: 764–770.

25
Q

What is the Global Vaccine Action Plan?

A

The Global Vaccine Action Plan 2011-2020 outlines strategies for immunization.

Strategic Advisory Group of Experts on Immunization, WHO; 2019.

26
Q

What document provides principles for adding a vaccine to a national immunization program?

A

WHO’s document outlines principles and considerations for vaccine addition.

April 2014.

27
Q

What does the study by Batayneh and Bdour focus on?

A

The study focuses on the immune status of adults and epidemiology for vaccination strategy in Jordan.

APMIS. 2002 Aug;110(7-8):528-34.

28
Q

What survey was conducted by the Department of Statistics in Jordan?

A

The Jordan Population and Family and Health Survey 2023 was conducted.

DoS and ICF, 2024.

29
Q

What does the study by MacDonald et al. recommend?

A

The study provides recommendations for the next decade of global vaccine action.

Vaccine. 2020 Jul 14;38(33).

30
Q

What is the focus of Hayajneh et al.’s study?

A

The study assesses the public health impact and cost-effectiveness of routine childhood vaccination for hepatitis A in Jordan.

BMC Infectious Diseases (2018) 18:119.

31
Q

Where can information on pneumococcal disease be found?

A

The CDC provides a chapter on pneumococcal disease.

32
Q

What does Paternina-Caicedo et al.’s study address?

A

The study addresses the impact of childhood vaccination on deaths in the 20th century in the US.

Biomédica: Revista del Instituto Nacional de Salud, Colombia.

33
Q

What is the focus of Akhtar et al.’s research?

A

The research discusses socioeconomic-related inequities in child immunization.

Health Econ Rev 14, 98 (2024).

34
Q

What do Gidengil et al. study?

A

They study parental perceptions related to co-administration of COVID-19 and routine vaccines.

Journal of Adolescent Health, Volume 72, Issue 5, pages 667-673 (May 2023).

35
Q

What is the focus of Baghdadi et al.’s study?

A

The study examines the impact of the COVID-19 pandemic lockdown on routine childhood immunization in Saudi Arabia.

Front. Pediatr. 9:692877.

36
Q

What do Essoh et al. explore?

A

They explore factors contributing to low vaccination uptake in Kenya.

BMC Public Health 23, 912 (2023).

37
Q

What does Jiang et al.’s scoping review cover?

A

The review discusses the coverage and challenges of increasing uptake of non-National Immunization Program vaccines in China.

Infect Dis Poverty 12, 114 (2023).

38
Q

What does Itiakorit et al. analyze?

A

They analyze the impact of COVID-19 on disparities in childhood immunization in low- and middle-income countries.

Curr Trop Med Rep 9, 225–233 (2022).