Vaccines

Question 1

What is an adjuvant?

Answer 1

compound that increases the immunogenicity of an antigen

Question 2

What is the most common adjuvant in vaccines?

Answer 2

aluminum salt Alum

Question 3

What is a live attenuated virus?

Answer 3

a weakened virus that can replicate to a limited extent

Question 4

Would you give MMR (measles, mumps, rubella) vaccine to a patient with a immunodeficiency disorder?

Answer 4

NO, can’t fight it off

Question 5

What is the difference between DPT and DTaP vaccines?

Answer 5

DPT is diptheria, tetanus and whole, killed pertussis antigen and DTaP replaced pertussis bacteria with acellular components (pertussis toxoid and alum)

Question 6

For what patients you just Tdap vaccine? What do the lower cases mean?

Answer 6

in adults and adolescents, means reduced concentration

Question 7

Why did the switch from DPT to DTaP occur?

Answer 7

killed pertussis was a very strong adjuvant that induced a strong innate immune response leading to severe fever in some cases

Question 8

What type of vaccine is MMR?

Answer 8

live attenuated vaccine

Question 9

What is RIG?

Answer 9

rabies immune globulin, passive immunization

Question 10

What is HDCV? PCECV?

Answer 10

human diploid cell rabies vaccine, purified chick embryo cell vaccine

Question 11

What do you give for someone previously immunized to rabies?

Answer 11

HDCV or PCECV on day 0 and 3

Question 12

What do you give for someone not immunized to rabies?

Answer 12

RIG near wound, HDCV or PCECV at different site on day 0,3,7,14