Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

nbme 21 > UWSA 1 > Flashcards

UWSA 1 Flashcards

1
Q

If you see an img of arthrocentesis with Ns but also crystals - irrespective of C/P!

A

its crystal arthropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Influenza drugs MOA?

A

Neuraminidase inhibitors - oseltamivir - stop release of newly formed virions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

An img on gel electrophoresis abt a 85 kDa protein that in 10,15,25 mins splits and gets thinner. Mechanism?

A

A single 85 kDa protein cleaved and modified subsequently

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

if some1 has sensations of crawling on skin, dry mucous memb, skin is warm, blurred vision. What substance abused?

Methyphenidate
Atropine

A

Its atropine cuz uk apart of crawling stuff, nothing fits methylphenidate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DM controlled + active individual. What is most recommended?

Daily foot inspection
Complex carb restriction

A

Foot inspection - check for trauma and infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

If pt has revealed tonns of info and he is drinking alcohol inc now. What shud u do?

A

Acknowledge and reflect - ki prolly u inc drinking as a way of coping with stress.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Review the heme pathway now!!!

A

Understand if a pt has abdominal pain, N/V, hepatomegaly. What enzyme? AIP

see this!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

If some1 with has a mass para-aortic at level of L4. Also has headache, palpitations and HTN + FLUSHING AND DIAPHORESIS.
what Dx?

Carcinoid
Adrenal

A

Adrenal!! obviooooooo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

OA pathogenesis?

A

degraded type 2 cartilage and proteoglycans.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Receptors for

Glucagon
Insulin
NE

A

Glucagon - Gs
Insulin - TK
NE - Gs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

A man with normal 2’ry sex characteristics and descended testis but low Tz conc in epididymis and seminiferous tubules. Defect kaha?

Leydig
Sertoli

A

Higher Tz conc in epididymis and seminiferous tubules maintained by Androgen-BP (produced by sertoli)

ans: sertoli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Pt has no known hx of blood issue but bby has hydrops fetalis. Peripheral smear shows?

Microcytes
Spherocytes
Sickle cell

A

Microcytes - seen in alpha and beta thalassemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

MSUD - mei a DH enzyme requires what co-factor?

A

B1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

If a female recipient has XY in here genome analysis post transplant of BM. Cause?

A

Male allogenic transplant donor - functional HSC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

cephalosporin mechanism of resistance?

A

Efflucx pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

After having Ag sample for ELISA. What to add?

A

Anti- IgG Abs + peroxidase
then latex particle to visualize

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Chronic hepC pt has inc HTN in what vein?

Portal
splenic

A

Splenic cuz portal vein is valveless!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Allelic heterogencity?

A

different mutations at a locus cause similar phenotypes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Genetic heterogenecity

A

same gene many mutations but similar phenotypes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Epistasis?

A

Multiple genes interact to create new phenotype that can mask or dec the symptoms of the actual disease.

Inc HbF in HbS

21
Q

Pleiotropy

A

Many phenotypes of same Dx – like Marfans effects BVs, eyes, skin etc

22
Q

Polygenic

A

can’t trace a spp gene that caused it

23
Q

Variable expressivity

A

difft phenotypes found in difft ppl effected with same disease

24
Q

Nitrates?

A

Inc HR (reflex)
dec EDV

only med that dec both is isopropanol

25
submandibular LN has SCC. Origin? Parotid Tongue LNs
Tongue
26
RB1 mechanism of mutation?
Loss of heterozygosity (Knudson's 2 hit hypothesis)
27
SCD?
C/P: DC, LCSTs, SCB tracts, peripheral nerve! B12 def! ALS - no sensory component effected!
28
MHC 2 making to cell memb what part is degraded?
Invariant chain is not expressed on the memb
29
Meningitis viral cause?
enterovirus, coxsackie too both are ssRNA +ve sense
30
what dec with inc sample samples size?
Standard error = SD/sample size
31
Unmyelinated nerve fibers?
autonomic post ganglionic pain and temp STT.
32
Rash + arthralgia + thin walled cavity in RLL. Cause of pneumonia? (Fever+ CP + hemoptysis + travel to south america)
Coccidiodes immitis
33
Li-Fraumani - gene and MOI>
AD - inactivating tp53 for 1 allele
34
Osteomalacia - what bone affected?
Osteoid mineralization affected.
35
Apoptotic cells DNA mech?
Internal ribosome entry - 5' untranslated region allows translation from mid
36
Gram -ve back spp ppy?
Have inner and outer memb Gram +ve have 1 PM only
37
Chromogrenin and synaptphysin +ve tumors?
always secrete SRT
38
Most imp RF for OA?
AGE!!! Not Fam Hx, smoking or wt bearing exercises
39
thin sclerae + visible choroid + scoliosis in 20 yr old who is athletic. What effected? Collagen Fibrillin
Collagen Fibrillin is okay but has CVS issues in qn stem like AA aneurysm n all
40
Anesthesia effects what band in muscle fiber to lengthen?
I band the overlap shortens when relaxed (H-band - effected in contraction where as here its relaxation)
41
Dec what inc contraction vel in CMs?
Afterload Preload + overlap btw the 2 proteins - initial muscle length b4 contraction Inc in passive tension - inc contaction vel + muscle length
42
Lung collapse 1st line trtmt?
CT placement to deflate the air off and then PEEP to inflate lungs
43
HIV nephropathy?
FSGS other causes: HbS, obese, INF and heroin Membranous nephropathy is HBV, HCV, NSAIDs, Penicillamine, Au, SLE
44
pt has HypoTN + cold hands + bleeding? Med given inc what? cGMP IP3
Alpha-1 blocker given - inc IP3 in sm muscle
45
CHD + seizures + low set ears + defect in chr 22. What effected?
Truncus arteriosis - persists in utero (Dx: Digeorge synd)
46
Prothetic valve pt long term Tx?
Warfarin
47
wt loss + smoking + shiny tongue (glossitis) + hyperpigmentation in axillae. Dx? Adrenal Gastric Ca
Gastric Ca
48
Denerved eye has contriction of pupil via?
Cholimimetic agent that works on papillary muscle - Pilocarpine
49
see img of sinus. The fluid in sinus till what level, waha ka issue?
Middle meatus!

nbme 21 (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions