UWorld Test Questions Flashcards

1
Q

What renal pathology has foci sclerosis and hyalinosis in some, but not all, glomeruli?

A

Focal segmental glomerulosclerosis

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2
Q

What renal pathology has mesangial proliferation on light microscopy with mesangial immune deposits of IgA on electron microscopy?

A

IgA nephropathy

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3
Q

What renal pathology has normal glomeruli on light microscopy, and diffuse effacement of podocytes on electron microscopy?

A

Minimal change disease

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4
Q

What renal pathology has glomerular crescents composed of proliferating parietal and inflammatory cells on light microscopy?

A

Rapidly progressive glomerulonephritis

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5
Q

What renal pathology has significant parenchymal ischemia that manifests as diffuse cortical tanning, tubular atrophy, and small crowded glomeruli?

A

Renal Artery Stenosis

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6
Q

What renal pathology has mesangial expansion, glomerular basement membrane thickening, and nodular glomerular sclerosis?

A

Diabetic nephropathy

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7
Q

What bone pathology shows radiographic findings of normal trabecular bone, mixed radio dense and radiolucent area, and periosteal new bone formation with lifting of the periosteum?

A

Osteosarcoma

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8
Q

What bone pathology shows radiographic findings with a crescent sign showing subchondral collapse at the femoral head?

A

Avascular necrosis

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9
Q

What bone pathology shows radiographic findings of osteophytes and joint-space narrowing?

A

Osteoarthritis

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10
Q

What bone pathology shows trabecular thinning and possible fractures and is increased risk in patients with corticosteroid exposure?

A

Osteoporosis

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11
Q

What bone pathology shows lytic or mixed/sclerotic lesions with cortical and trabecular thickening?

A

Paget’s disease of the bone

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12
Q

What hematologic disease has round nuclei with basophilic cytoplasm containing prominent lipid vacuoles?

A

Burkett’s lymphoma t(8;14)

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13
Q

What hematologic disease shows leukocytosis with many immature myeloid cells (myelocytes)?

A

CML t(9;22)

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14
Q

What hematologic disease shows anemia, thrombocytopenia, and lymphoblasts?

A

ALL t(12;21)

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15
Q

What hematologic disease shows malignant cells with notches or clefts (centrocytes)?

A

Follicular lymphoma t(14;18)

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16
Q

What hematologic disease shows azurophilic, needle-shaped cytoplasmic inclusions?

A

APL (auer rods) t(15;17)

17
Q

What dermatologic condition consists of enlarged cells with intranuclear inclusions that fuse into ballooning multinucleate giant cells that ulcerate and form a crust?

A

Herpes simplex

18
Q

What dermatologic condition consists of have slow-growing papule with an ulcerated or rolled border with histopathology that shows nests or strands of basaxoid cells with hyper chromatic nuclei with peripheral palisading?

A

Basal cell carcinoma

19
Q

What dermatologic condition consists of non-umbilicate, skin-colored or pink papule and growths that show undulating epidermal hyperplasia with enlarged nuclei and cytoplasmic vacuolization (koilocytosis) that form perinuclear halos?

A

Verruca vulgaris

20
Q

What dermatologic condition consists of epidermal hyperplasia along with molluscum bodies with large cytoplasmic inclusions with papules that are pruritic with umbilicate centers of white, curd-like material?

A

Molluscum contagiosum

21
Q

What chemotherapy agent is known for causing ototoxicity?

22
Q

What GI pathology shows cobblestone mucosa and transmural inflammation?

A

Crohn’s Disease

23
Q

What GI pathology shows crypt accesses and multiple pseudopolyps?

A

Ulcerative colitis

24
Q

What GI pathology shows neoplastic cells infiltrating beyond the lamina propria?

A

Colonic adenocarcinoma

25
What GI pathology do macrophages with PAS-positive granules suggest with accompanying blood in the stool?
Whipple's disease
26
What GI pathology is strongly associated with cardiovascular disease and shoes mucosal hemorrhage, ecchymoses, and patchy necrosis?
Ischemic colitis