UWorld Test Questions Flashcards
What renal pathology has foci sclerosis and hyalinosis in some, but not all, glomeruli?
Focal segmental glomerulosclerosis
What renal pathology has mesangial proliferation on light microscopy with mesangial immune deposits of IgA on electron microscopy?
IgA nephropathy
What renal pathology has normal glomeruli on light microscopy, and diffuse effacement of podocytes on electron microscopy?
Minimal change disease
What renal pathology has glomerular crescents composed of proliferating parietal and inflammatory cells on light microscopy?
Rapidly progressive glomerulonephritis
What renal pathology has significant parenchymal ischemia that manifests as diffuse cortical tanning, tubular atrophy, and small crowded glomeruli?
Renal Artery Stenosis
What renal pathology has mesangial expansion, glomerular basement membrane thickening, and nodular glomerular sclerosis?
Diabetic nephropathy
What bone pathology shows radiographic findings of normal trabecular bone, mixed radio dense and radiolucent area, and periosteal new bone formation with lifting of the periosteum?
Osteosarcoma
What bone pathology shows radiographic findings with a crescent sign showing subchondral collapse at the femoral head?
Avascular necrosis
What bone pathology shows radiographic findings of osteophytes and joint-space narrowing?
Osteoarthritis
What bone pathology shows trabecular thinning and possible fractures and is increased risk in patients with corticosteroid exposure?
Osteoporosis
What bone pathology shows lytic or mixed/sclerotic lesions with cortical and trabecular thickening?
Paget’s disease of the bone
What hematologic disease has round nuclei with basophilic cytoplasm containing prominent lipid vacuoles?
Burkett’s lymphoma t(8;14)
What hematologic disease shows leukocytosis with many immature myeloid cells (myelocytes)?
CML t(9;22)
What hematologic disease shows anemia, thrombocytopenia, and lymphoblasts?
ALL t(12;21)
What hematologic disease shows malignant cells with notches or clefts (centrocytes)?
Follicular lymphoma t(14;18)
What hematologic disease shows azurophilic, needle-shaped cytoplasmic inclusions?
APL (auer rods) t(15;17)
What dermatologic condition consists of enlarged cells with intranuclear inclusions that fuse into ballooning multinucleate giant cells that ulcerate and form a crust?
Herpes simplex
What dermatologic condition consists of have slow-growing papule with an ulcerated or rolled border with histopathology that shows nests or strands of basaxoid cells with hyper chromatic nuclei with peripheral palisading?
Basal cell carcinoma
What dermatologic condition consists of non-umbilicate, skin-colored or pink papule and growths that show undulating epidermal hyperplasia with enlarged nuclei and cytoplasmic vacuolization (koilocytosis) that form perinuclear halos?
Verruca vulgaris
What dermatologic condition consists of epidermal hyperplasia along with molluscum bodies with large cytoplasmic inclusions with papules that are pruritic with umbilicate centers of white, curd-like material?
Molluscum contagiosum
What chemotherapy agent is known for causing ototoxicity?
Cisplatin
What GI pathology shows cobblestone mucosa and transmural inflammation?
Crohn’s Disease
What GI pathology shows crypt accesses and multiple pseudopolyps?
Ulcerative colitis
What GI pathology shows neoplastic cells infiltrating beyond the lamina propria?
Colonic adenocarcinoma
What GI pathology do macrophages with PAS-positive granules suggest with accompanying blood in the stool?
Whipple’s disease
What GI pathology is strongly associated with cardiovascular disease and shoes mucosal hemorrhage, ecchymoses, and patchy necrosis?
Ischemic colitis
