UWorld pearls Flashcards
HIT pathophys?
heparin causes conformational change on platelet surface protein (platelet factor 4) –> neoantigen exposed –> HIT antibodies form –> platelets aggregate
HIT diagnostic test?
immunoassay or functional assay (5-HT release assay)
What anticoag can cause protein C deficiency?
warfarin
What does protein C deficiency look like?
skin necrosis
Polycythemia vera tx?
phlebotomy
Uric acid stone prevention?
lots of fluids and potassium citrate
Name the 2 radiolucent stones.
uric acid, xanthine
Why potassium citrate in uric acid stones?
to alkalinize the urine, which makes the stones soluble
Best non-pharm BP tx?
DASH diet
Hairy cell leukemia diagnostic test?
bone marrow biopsy, flow cytometry
OD: hypoTN, bradycardia, diffuse bilateral wheezing, 1st degree AV block. Dx?
beta-blocker OD
Tx beta-blocker OD?
airway, fluids, IV atropine, IV glucagon
Dx? myopathy with anxiety, tachycardia, weight loss, fatigue
thyrotoxic myopathy (hyperthyroidism)
Pleural fluid protein / serum protein ratio in exudate?
> 0.5
Pleural fluid LDH / serum LDH in exudate?
> 0.6