UWorld Assessment 2 Flashcards

1
Q

Rside heart failure, treated with furosemide, now has AKI, d/t?

A

Intravascular depletion

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2
Q

Patient has 44 lb weight loss, BMI 19, amenorrhea
No bleeding on progesterone challenge
Cause?

A

Functional hypothalamic amenorrhea

No withdrawal bleeding d/t low endogenous levels of estrogen

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3
Q

Abdominal pain, nausea, vomiting, post op day 4 cholecystectomy
Elevated bilirubin
DX?

A

Biliary leak

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4
Q

CSF has increased protein level with normal cell count, dx?

A

Gillian-Barre syndrome

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5
Q

Rett syndrome gene

A

MECP2

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6
Q

Hemodynamics in cardiogenic shock

A
Increase CVP
Increase PCWP
Decrease CI
Increase SVR
Decrease SvO2
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7
Q

1 day old with petechiae, jaundice, hepatosplenomegally, microcephaly

Etiology?

A

CMV

Also hearing loss, periventricular calicifications

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8
Q

Management of threatened abortions

A

Observation and repeat ultrasound

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9
Q

Conjunctivitis, foreign body sensation, increased vascularity

Normal pupillary reflexes, visual acuity, fungus optic exam

Dx?

A

Ocular rosacea

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10
Q

How to decrease postop pneumonia?

A

Preop physical therapy
Smoking cessation >8 weeks
Spirometry postop

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11
Q

Watery diarrhea with blood and mucus
No response to cipro
LLQ tenderness
Philippines trip

Dx? How? Tx?

A

Entamoeba histolytica colitis by stool microscopy

Metronidazole

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12
Q

Treatment of severe hypercalcemia

A

Normal saline plus calcitonic, avoid loop diuretics

Long term: bisphosphonate

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13
Q

28 y/o with severe pneumonia, ICU for 4 days, now yellow sputum streaked with blood
Crackles in R lower lung and scattered wheezing

Dx? Pathophys?

A

Bronchiectasis d/t permanent destruction and dilation of the airways

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14
Q

68 y/o male, decreased hearing in R eye
Increased hat size over 2 years
Increased ALP
X-rays: sclerotic and lytic lesions

Dx? Pathophys?

A

Paget disease d/t disorganized bone remodeling

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15
Q

When to deliver in preeclampsia without severe features

A

> 37 weeks

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16
Q

When to deliver in preeclampsia with severe features

A

> 34 weeks

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17
Q

When to deliver in eclampsia

A

Immediately

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18
Q

What features define preeclampsia with severe features

A

Can have only 1

```
>160/>110
Scotoma
Headache
Thrombocytopenia
Elevate liver enzymes
Elevated Cr
End organ damage
~~~

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19
Q

Steps of failure modes and effects analysis

A
Get an interdisciplinary team
Define goals and process
Process mapping
Id failure modes
Hazard analysis
Action plain
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20
Q

Timing of RV failure after MI

What vessel

A

Acute

RCA

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21
Q

Timing of papillary muscle rupture after MI

What vessel

A

Acute or within 3-5days

RCA

22
Q

Timing of interventricular septum rupture after MI

What vessel

A

Acute or within 3-5 days

RCA or LAD

23
Q

Timing of free wall rupture after MI

What vessel

A

Within 5 days - 2 weeks

LAD

24
Q

Timing of LV aneurysm after an MI

What vessel

A

Up to several months

LAD

25
Q

HIV, several months of anal pain and bleeding, anal ulcer, painless lymphadenopathy

DX?

A

Anal cancer d/t HPV

26
Q

In LGV d/t Chlamydia trachomatis, lymphadenopathy is…

The ulcer is…

A

Painful

Non tender

27
Q

Pregnant patient with fever, chills, SOB, blank pain
Diffuse bilateral crackles
R flank tenderness
Cervix 1 cam, contractions q 5 min

Dx?

A

Acute pyelonephritis complicated by ARDS and preterm labor

28
Q

Child comes in for acute mastoiditis, what’s next

A

IV ab’s

Do not need imaging unless complications

29
Q

In antiphospholipid antibiody syndrome, PTT is (short/prolong)

What antibodies?

A

Prolonged (even though they are prothombotic)

Anti-beta-2-glycoproteins 1, antiphophatidylserine, anticariolipin

30
Q

Painless ulcer on penis for months, inguinal lymphadenopathy, smoker

Dx?

A

Penile cancer

31
Q

Loss of peripheral vision

A

Open angle glaucoma

32
Q

Anticoagulation in pregnancy

A

LMWH

33
Q

What is DRESS Syndrome?

A

Drug: MC allopurinol and anti epileptics
Reaction: morbiliform eruption, starts on face—> diffuse
Eosinophilia
Systemic symptoms: fever, malaise, diffuse lymphadenopathy, organ involvement

34
Q

Latency of DRESS syndrome

A

Long, 2-8 weeks

35
Q

Tx of DRESS syndrome

A

Stop drug, supportive care

36
Q

Was in Panama
Took chloroquine for malaria
Now symptoms are back

Etiology, why? What additional therapy?

A

P. Vivax, dormant period, add primaquine to attack dormant hepatic phase

37
Q

AUB, pelvic pressure, symmetrically enlarged uterus, friable vaginal lesion
Spontaneous abortion 6 months ago
DX?

A

Choriocarcinoma with vaginal metastasis

38
Q

Time difference between MDD and GAD

A

MDD: >2 weeks
GAD: >6 mo

39
Q

Palpable thrill accompanied by harsh holosystolic murmur in 4th L ICS

A

VSD

40
Q

15 month old refusing to bear weight on R leg
URI 2 weeks ago, Born breech
Hip external rotated, cries when moved
T 102.6, 19,800 leukocyte, ESR 55

Dx? D/t?

A

Septic arthritis d/t hematogenous bacterial spread into joint space

41
Q

MC etiology of septic arthritis

A

S. Aureus and GAS

42
Q

Single most effective strategy to prevent acquiring HSV?

A

Consistent condom use

43
Q

Patient took multiple meds for migraine, now can’t sit and needs to walk

Side effect d/t?

A

Prochlorperazine, akathisia

44
Q

To start isotretinoin, what do you need and what does the patient need to do

A

2 negative pregnancy tests
And
2 forms of contraception

45
Q

Initial approach to behavioral regression after birth of younger sibling

A

Spend 1-on-1 time

46
Q

Patient on carbamazepine, now has nausea, forgetfulness
Na 125

Dx?

A

SIADH d/t side effect of carbamazepine

47
Q

Serum osm, urine osm, urine Na in setting of SIADH

A

Low, high, high (>40)

48
Q

Lung cancer with cavitary lesion

A

Squamous cell carcinoma

49
Q

4 y/o has URI resolve 2 days ago
Now has ataxia, horizontal nystagmus for several hours
Dx?

A

Acute cerebellar ataxia

50
Q

Pathophys of direct inguinal hernia

A

Weakening of inguinal canal floor

51
Q

Pathophys of indirect inguinal hernia

A

Failure of processes vaginalis closure

52
Q

First line tx for gentian warts for pregnant women

A

Topical trichloroacetic acid