uWise Facts Flashcards
1
Q
Contraindications to expectant management of Pre-E w/SF
A
- All deliver @ 34 weeks at latest
- contraindications to expectant management prior to 34 weeks
- thrombocytopenia
- pulmonary edema
- renal failure
- abruption- placentae
- disseminated intravascular coagulation
- persistent cerebral symptoms
- non-reassuring fetal testing
- fetal demise.
2
Q
- Dx?
- hirsutism, irregular menses and obesity
- patient’s hirsutism has worsened
- depressed
- She has also gained 20 pounds in the past two months and has noticed purple stretch marks
- terminal hair growth on her chin and hair growth on the back of her hands.
- Her cheeks appear flushed
A
Cushing’s syndrome likely
3
Q
Contraindications to using a patch
A
weight > 198 lbs
4
Q
Weight necc. for menses to begin
A
85 to 106 poinds
5
Q
Inpatient tx of PID
A
- options parenteral antibiotics covering both gonorrhea and chlamydia
- Cefotetan or cefoxitin PLUS doxycycline
- clindamycin PLUS gentamicin
6
Q
Outpatient tx of GC/CT
A
- For outpatient treatment, the 2010 CDC guidelines recommend:
- ceftriaxone, cefoxitin, or other third-generation cephalosporin (such as ceftizoxime or cefotaxime)
- PLUS doxycycline
- WITH or WITHOUT metronidazole.
7
Q
Criteria for PMDD
A
- PMDD is a psychiatric diagnosis, describing a severe form of premenstrual syndrome
- diagnostic criteria include five out of 11 clearly defined symptoms, functional impairment
- prospective charting of symptoms present during the last week of the luteal phase that begin to resolve with the beginning of the follicular phase
- All three areas of symptoms need to be represented for the diagnosis of PMDD.
8
Q
Menstrual cycle overview
A
- Days 0-14 = follicular phase
- Days 14-28 = luteal phase
9
Q
Tx of mastitis
A
- anti-staphylcoccal agent
- Dicloxacillin is used due to the large prevalence of penicillin resistant staphylococci
- Erythromycin may be used in penicillin allergic patients.
- Doxycycline, gentamicin, and cefotetan are not appropriate antibiotics for treatment of mastitis.
10
Q
Source of estrogen in postmenopausal women
A
- Estrogen production by the ovaries does not continue beyond menopause.
- estrogen levels in postmenopausal women can be significant due to the extraglandular conversion of androstenedione and testosterone to estrogen
- This conversion occurs in peripheral fat cells and, thus, body weight has been directly correlated with circulating levels of estrone and estradiol.
- Since menopausal ovaries are known to continue production of androgens, surgical removal of postmenopausal ovaries may result in the resurgence of menopausal symptoms from the abrupt drop in circulating androgens.
11
Q
Characteristifs of Postpartum telogen effluvium (hair loss)
A
- affects 40-50% of women postpartum
- High estrogen levels in pregnancy increase the synchrony of hair growth (hair growth normally asynchronous)
- ==> hair grows in the same phase and is shed at the same time.
- ==> significant postpartum hair loss at 1 to 5 months postpartum
12
Q
Tx of urge incontinence
A
- urge incontinence = detrusor instability
- acetylcholine is the transmitter that stimulates the bladder to contract through muscarinic receptors
- Thus, anticholinergics are the mainstay of pharmacologic treatment
- Oxybutynin is one example
13
Q
Control of prolactin production
A
- inhibited by dopamine
- dopamine antagonists ==> elevated prolactin
- antipsychotics, TCAs, MAOIs
- dopamine antagonists ==> elevated prolactin
- stimulated by TRH and serotonin
- hypothalamic and pituitary tumors ==> increased prolactin
14
Q
Cervical mucuous at various phases of menstrual cycle
A
- early follicular phase (just after menstruation) = thick, scant, acidic
- ovulatory phase = clear and thin
- stetches (to 6cm)
- more basic than other phases; pH>6.5
- mid-late luteal phase =
- ovulation already occured
- thicker, less stretching ability
- inhospitable to sperm
15
Q
Paget’s disease of breast associated with…
A
adenocarcinoma of the breast
