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X Kanski synopsis for Duke > Uveitis > Flashcards

Uveitis Flashcards

1
Q

ant uveitis

A

iritis

iridocyclitis

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2
Q

iridocyclitis?

A

iris + pars plicata

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3
Q

intermediate uveitis

A

pars plana

extreme periphery

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4
Q

posterior uveitis

A

choroid

retina post to vitreous base

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5
Q

acute uveitis

A

up to 3 months

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6
Q

chronic uveitis

A

longer than 3 months

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7
Q

uveitis causes

A

systemic
infection
infestation
idiopathic non/specific

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8
Q

acute ant uveitis

presentation

A 
photophobia
pain
redness
decreased vision
lacrimation
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9
Q

acute ant uveitis

signs

A

ciliary injection
endothelial dusting w/ inflam cells
aqueous cells + flare
fibrinous exudate + hypopyon

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10
Q

acute ant uveitis

grading use

A

aqueous cells + flare

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11
Q

acute ant uveitis

causes

A 
HLA-B27 PAIR
UC/Crohns
sarcoidosis
behcet
herpes zoster
syphilis
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12
Q

chronic ant uveitis

PC

A

mild redness + floaters

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13
Q

chronic ant uveitis signs

A

KP = keratic precipitates
mutton-fat KP
Iris nodules Koeppe at middle, Busacca at periphery

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14
Q

chronic ant uveitis

comp

A 
post synechiae
band keratopathy
glaucoma
macular oedema + EPM
Cyclitic membrane + phthisis bulbi
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15
Q

chronic ant uveitis

causes

A 
Fuchs uveitis
sarcoid
JIA
VKH
TB
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16
Q

Intermediate uveitis

PC

A

floaters

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17
Q

Intermediate uveitis

signs

A

mild ant uveitis
vitreous cells
peripheral retina periphlebitis
inf snowbanking in pars planitis

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18
Q

Intermediate uveitis

comp

A

cataract
CMO
Cyclitic membrane
retinal detachment

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19
Q

Intermediate uveitis

causes

A 
idiopathic
sarcoid
MS
Lyme
Whipple
Cat scratch fever
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20
Q

posterior uveitis

Sx

A

floaters

visual impairment

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21
Q

posterior uveitis

signs

A 
spill over ant U
Vitritis
choriditis - doesn't obscure retinal vessels
retinitis - obscure retinal vessels
vasculitis
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22
Q

posterior uveitis

morphology

A

focal
multifocal
geographic

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23
Q

posterior uveitis

comp

A 
maclar oedema/ ischaemia
ERM
vascular occlusion
CNV
Retinal detachment
optic neuropathy
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24
Q

posterior uveitis

causes

A 
toxoplasmosis
sarcoid
behcet
CMV
toxocariasis
histoplasmosis
VKH
Birdshot retinochoroidopathy
25
Q

uveitis tx drug classes

A

mydriatics
steroids
immunosuppressives

26
Q

mydriatics prep

A

short-acting
tropicamide
cyclopentate
phenylephrine

long acting
atropine

27
Q

mydriatics indications

A

comfort relieve ciliary/ pupillary spasm

prevent/ breakdown post synechiae

28
Q

steroid topical for

A

acute + chronic ant uveitis

29
Q

steroid comp

A 
glaucoma
cataract
secondary microbial keratitis
herpes simplex keratitis comes back
corneal melting
30
Q

periocular steroids for

ant/ post sub-Tenon

A

severe acute ant u
adjunct to topical/systemic in resistant chronic ant u
intermediate u
poor compliance

31
Q

systemic steroids for

A

panuveitis

ant/ intermediate u not responding to sub-Tenon injections

32
Q

systemic steroid short term comp

A

dyspepsia
mental changes
aseptic necrosis of femoral head
hyperosmolar hyperglycaemic non-ketotic coma

33
Q

systemic steroid long term comp

A 
cushings
osteoporosis
limit growth in kids
reactivate TB
Cataract
worsen DM
34
Q

immunosuppressives EG

A 
Azathioprine
methotrexate
cyclosporin
tacrolimus
mycophenalate mofetil
35
Q

Azathioprine for

A

behcets

36
Q

Azathioprine SEs, monitoring

A

bone marrow suppression
GI upset
hepatotox

FBC every 4-6 wks
LFTs every 12 wks

37
Q

methotrexate for

A

steroid resistant non infectious u

38
Q

methotrexate SEs, monitoring

A

bone marrow suppression
GI upset
hepatotox
pneumonitis

FBC, LFT every 1-2 months

39
Q

cyclosporin for

A

behcets
VKH
Birdshot retinopathy
sympathetic ophthalmitis

40
Q

cyclosporin SEs, monitoring

A 
HTN
Nephrotox
hepatotox
hirsuitism
gingival hyperplasia

BP, FBC, RFT, LFT every 6 wks

41
Q

tacrolimus for

A

alternative to cyclosporin

42
Q

tacrolimus SEs, monitoring

A 
HTN
Nephrotox
GI upset
hyperglycemia
neurological

weekly BP, Renal + glucose at first

43
Q

mycophenalate mofetil for

A

indications not established!

44
Q

mycophenalate mofetil SEs, monitoring

A

BM suppression
GI upset

FBC weekly for 4 wks

45
Q

ank spon is found

A

in 30% of patients with acute ant uveitis

46
Q

what other eye problems do ank spon pts have?

A

conjunctivitis
peripheral corneal infiltrates
papillitis

47
Q

what % of Reiters pts have acute ant uveitis

A

20%

48
Q

what other eye problems do Reiters pts have?

A

conjuncitivitis

punctate epithelial keratitis

49
Q

what % of psoriatic arthritis pts have acute ant uveitis

A

10%

50
Q

what other eye problems do psoriatic arthritis pts have?

A

conjunctivitis
raised corneal infiltrates
secodary sjögrens

51
Q

JIA uveitis signs

A

aSx

small-medium KP

52
Q

JIA uveitis Prognosis

A

25% mild
50% moderate but responds to tx
25% severe –> band keratopathy, cataract, glaucoma, phthisis bulbi

53
Q

JIA uveitis high risk

A

onset before age 6
pauciarticular disease <5 joints
+ ANA

54
Q

JIA uveitis MEDIUM risk

A

polyarticular disease >4 joints, + ANA

pauciarticular disease <5 joints, - ANA

55
Q

JIA DDx

A 
juvenile AS
juvenile Reiters (post-dysenteric)
juvenile psoriatic arthritis
sarcoidosis
lyme
56
Q

what % of UC pts have acute ant uveitis

A

5%

57
Q

what % of crohns pts have acute ant uveitis

A

3%

58
Q

other UC ocular problems?

A

conjuncitivitis
peripheral corneal infiltrates
papillitis

59
Q

other Crohns ocular problems?

A

conjuncitivitis
episcleritis
peripheral corneal infiltrates
retinal periphlebitis

X Kanski synopsis for Duke (2 decks)

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