Uveitis Flashcards

1
Q

def

A

intraocular inflammation of both the uveal tract and neighbouring structures (retina, vitreous, optic nerve)

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2
Q

what is the uveal tract

A

middle layer of the wall of the eye

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3
Q

what are the three main parts of the uveal tract

A
1 choroid (later filled with blood vessels)
2 ciliary body (ring of muscle which changes the size of the pupil and the shape of the lens)
3 the iris (coloured part of the eye)
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4
Q

what is the uvea

A

AKA as the uveal tract

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5
Q

epi

A

common

anterior uveitis > posterior uveitis

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6
Q

risk factors/associations

A

1 systemic inflammatory diseases such as juvenile idiopathic arthritis, RA, IBD

half of ankylosing spondylitis patients develop anterior uveitis

2 HLA B27 positive

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7
Q

what are the different classifications of uveitis

A

anterior (most common)

posterior

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8
Q

what is inflamed in anterior uveitis

A

anterior chamber

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9
Q

what is inflamed in posterior uveitis

A

retina or choroid

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10
Q

aetiology of anterior uveitis

A

1 infection (HSV, VSV)
2 as aa manifestation of systemic inflammatory conditions (juvenile idiopathic arthritis, HLA B27 spondyloarthritides such as ankylosing spondylitis, RA, IBD)
3 sarcoidosis
4 behcets disease

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11
Q

what is behcets disease

A

vasculitis

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12
Q

aetiology of posterior uveitis

A
1 infection (CMV, TB)
2 systemic inflammatory conditions (sarcoidosis)
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13
Q

history of anteior uveitis

A

dull pain in anterior uveitis which gets worse on accommodation (there is no pain in posterior uveitis)
redness, watering, blurred vision

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14
Q

history of posterior uveitis

A

no pain
blurred vision
floaters

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15
Q

examination

A

1 small irregular pupil
2 decreased visual acuity
3 slit lamp looking for keratic precipitates which are deposits of leukocytes on the corneal endothelium

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16
Q

what are complicationa of uveitis

A
increased IOP (glaucoma)
cataracts
17
Q

investigations

A

diagnosis made on history and clinical examination

however investigate for associated systemic conditions like spondyloarthritides (SI joint x-ray), HLA-B27, sarcoidosis