Uveitis Flashcards
uvea
vascular middle coat of the eye made of the
- iris
- choroid
- ciliary body
what makes up the anterior uvea?
iris
ciliary body
What makes up the blood aqueous barrier?
Tight junctions b/w
- endothelial cells of iris vasculature
- nonpigmented epithelium of ciliary body
what is the term for inflammation of the iris?
iritis
Inflammation of iris and ciliary body
Iridocyclitis
inflammation of the whole uvea
Panuveitis
Inflammation of uveal tract and ocular cavities
Endophthalmitis
inflammation of all 3 tunics of the eye (nervous, vascular, fibrous)
Panophthalmitis
What are three effects of inflammation on the uveal tract?
vessels dilate
vessels leak
breakdown of BAB
What are important inflammatory mediator involved in uveitis? What is caused?
PG (especially PGF2alpha)
- Hyperemia
- Decreased IOP
- Miosis
- Pain (squinting, tearing, photophobic)
Leukotrienes: chemotactic
What is the hallmark of uveitis?
Aqueous flare
What is aqueous flare?
Increased protein in anterior chamber (proteins from vessel damage)
Term for pus in the eye
Hypopyon
Term for blood in the eye
Hyphema
What are keratic precipitates?
inflammatory cells stuck in the cornea
What are some chronic signs of inflammation?
- cataracts
- posterior synechia
- deep corneal vascularization
- iris bombe
- lens luxation
- secondary glaucoma
- phthisis bulbi
what is posterior synechia?
iris adherent to anterior lens capsule
Looks like iris has been smeared on lens