UTI & STIs Flashcards
Most common cause of uncomplicated UTI?
E. Coli
Urease producer of uncomplicated UTI?
P. mirabilis
Who is an uncomplicated UTI patient?
Healthy, non-pregnant adult female
Gram (-) cause of complicated UTI
P. aeruginosa
G (+) urease producer that can cause complicated UTI
S. Saprophyticus
Pathology of UTI
Ascending - usu. E. Coli from GI or iratrogenesis
Complicated UTI patient?
DM, pregnant, Hx pyelo, Sx > 7days before Tx, MDR, HAP, renal failure, HX UTI as a child
STI cause of a UTI
C. trachomatis/ N. gonorrhea
Tx UTI
Bactrim…then Cipro
Tx pyelonphritis
Cipro/Levo
Spirochete with slow rotational motility; produces AB’s to somatic proteins and cardiolipin of host mitochondrial membranes
T. pallidum
What org causes syphilis
T. pallidum
VF of T. pallidum
membrane protein = adhesion, fibronectin, hyaluronidase
Chancre with smooth base, raised border that is firm and indurated; painless
syphilis chancre
Which stage is the chancre in syphilis
primary (entry stage)
The stage of syphilis that is the highly infectious stage; Latent stage; maculopapular rash (can spread to palms)
secondary stage
Stage of syphilis where there are neuro sx, cardio sx, granuomata systemic
tertiary stage: usu 5-20 years later
Dx Syphilis
Chancre; Dark field micro for treponemes; Nontreponemal: cardiolipin flocculation test; Treponemal: specific AB tests
Hutchinson’s Triad
notched incisors, keratitis, 8th nerve deafness (congenital syphilis)
Syphilis lesions primarily due to
cytokines = inflammation
G(-) kidney-beaned shaped cells; fastidious growth
N. gonorrhoeae