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Renal > UTI. Large Group 6 -Pumy > Flashcards

UTI. Large Group 6 -Pumy Flashcards

1
Q

Which of the following offers the LOWEST propensity for collateral damage?

A. ciprofloxacin
B. cefepime
C. trimethoprim-sulfamethoxazole
D. ampicillin
E. nitrofurantoin
A

E. nitrofurantoin

good for uncomplicated UTIs b/c little effect on normal fecal flora to get resistance

not good in suspected pyelo*

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2
Q

Which of the following is MOST LIKELY to cover Pseudomonas aeruginosa?

A. ceftriaxone
B. nitrofurantoin
C.ertapenem
D. trimethoprim-sulfamethoxazole
E. piperacillin
A

E. piperacillin (at higher doses than normally given)

cefepime also covers pseudomonas

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3
Q

What is a 3rd generation cephlosporin that covers pseudomonas?

A

cephtazedine

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4
Q

Which of the following concentrates BEST in prostatic tissues?

A. ceftriaxone
B. imipenem-cilastatin
C. trimethoprim-sulfamethoxazole
D. piperacillin-tazobactam
E. nitrofurantoin
A

C. trimethoprim-sulfamethoxazole

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5
Q

A 30-year-old female presents with suspected acute, uncomplicated pyelonephritis. Fluoroquinolone-resistance amongst community uropathogenic E. coli is ~5%. She has no known drug allergies. Which of the following would be the MOST APPROPRIATE empirical regimen pending culture results?

A. amoxicillin
B. ciprofloxacin
C. nitrofurantoin
D. ceftriaxone
E. ampicillin
A

B. ciprofloxacin

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6
Q

A 30-year-old female presents with suspected acute, uncomplicated pyelonephritis. Fluoroquinolone-resistance amongst community uropathogenic E. coli is 25%. She has no known drug allergies. Which of the following would be the MOST APPROPRIATE empirical regimen pending culture results?

A. amoxicillin
B. ciprofloxacin
C. nitrofurantoin
D. ceftriaxone
E. ampicillin
A

D. ceftriaxone

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7
Q

In a pt with DM, RTA, community acquired acute pyelo and hyperkalemia, what is the best choice?

A. nitrofurantoin 
B. ciprofloxacin 
C. gentamicin  
D. cefepime
E. trimethoprim-sulfamethoxazole
A

D. cefepime

covers both pseudomonas and enterobactericeae and is bactericidal (Beta lactam so it damages cell walls)

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8
Q

What does UPEC have that is required for it to attach to the bladder?

A

Type I pili bind to alpha methyl D mannosides on glycoproteins

and P pili that attach to the gal-gal on ureter and kidney urothelial cells

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9
Q

What is the best treatment for acute, uncomplicated cystitis?

A

5 day course of nitrofurantoin

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10
Q

What do WBC casts indicate?

A

pyelonephritis

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11
Q

How can you determine if a pt has developed a complication of a UTI? What are these possible complications?

A

imaging–> CT, US

bacteremia

emphysematous cystitis and pyelonephritis (gas pocket)

renal abscess

papillary necrosis

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12
Q

What can be given to prevent recurrent UTIs in a pt with chronic prostatitis?

A

Daily bedtime nitrofurantoin for 6 months

not targeting prostate but the bacteria that leaves the prostate

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Renal (9 decks)

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