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pharma Omamah > UTI > Flashcards

UTI Flashcards

1
Q

TMP/SMX DF

A

Oral

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2
Q

TMP/SMX spectru,

A

Aerobic enteric bacteria except P.aeru

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3
Q

TMP/SMX use

A

Prophylaxis for recurrent

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4
Q

Nitrofurantoin DF

A

Oral

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5
Q

Nitrofurantoin use

A

Therapeutic & prophylaxis

Cystitis & recurrent

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6
Q

Fosfomycin DF

A

Oral as single dose

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7
Q

Fosfomycin use

A

Uncomplicated infection —> cystitis but not pyelonephritis

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8
Q

UTI drugs with low resistance

A

Nitrofurantoin & fosfomycin

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9
Q

FQ DF

A

Oral

IV

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10
Q

FQ spectrum

A

Greater spectrum than others w/P.aeru

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11
Q

FQ use

A

Pyelonephritis

Prostatitis

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12
Q

FQ Cautions

A
  1. Not in preg
  2. Not in Children
  3. Moxi not used due to lack of urinary conc
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13
Q

Penicillin used in UTI & their DF

A
  1. Amox-clav - oral
  2. amp-sul - IV
  3. Pip-tazo - IV
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14
Q

Amox-clav use

A

Preferred penicillin for uncomplicated cystitis

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15
Q

Amp-sul & pip-tazo spectrum

A

More act ag P.aeru and entero and are preferred over cephalosporins

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16
Q

In which patients are Amp-sul & pip-tazo useful

A
  1. Renally impaired pts

2. Amino glycoside is to be avoided

17
Q

Cefalexin
Cefaclor
Cefpodoxime-proxetil

A

Useful in cases of resistance

Not act ag entero

ORAL

18
Q

Ceftriaxone
Ceftazidime
Cefepime

A

Act ag p.aeru

IV

19
Q

Use of 3rd & 4th cephalosporins

A

Nosocomial infections

Urosepsis

20
Q

Carbapenems / monobactms DF

A

IV

21
Q

Carbapenems spectrum

A

Broad including gram positive / gram negative / anaerobic

P.aeru except ertapenem

22
Q

Aztreonam spectrum

A

gram-negative bacteria, including some strains of P.

aeruginosa .

23
Q

Aztreonam uses

A

Nosocomial infections when AG are to be avoided & in penicillin sens pts

25
Q

Aminoglycosides Gentamicin, Tobramycin, Amikacin DF

A

IV

26
Q

Acute simple cystitis treatment ?

A
  1. Nitrofurantoin
  2. TMP/SMX
  3. trimethoprim
  4. Fosfomycin
27
Q

Alternatives in acute simple cystitis

A
  1. Amoxicillin/clavulanate
    2 cephalosporins oral
  2. FQ

Duration longer bcz not as effective as 1st lines

28
Q

Recurrent infections?

A

Nitrofurantoin
TMP/SMX

6 months

29
Q

Acute simple cystitis / asymptomatic bacteriuria (ASB) in pregnancy

A 
1 nitro
Amox-clav 
Cephalexin
Cefopodoxime 
Fosfo
TMP/SMX
30
Q

What are the drugs avoided in 1st trimester?

A

Nitro & TMP/SMX

31
Q

Acute uncomp pyelo / acute comp cystitis

A

if out patient
Floxacins

If local FQ resistance is > 10%, give ceftriaxone 1 g IV once or a dose of an AG (pending culture results)

Then alternatives:
TMP/SMX
Cefpodoxime
Amox-clav

Give ceftriaxone 1 g IV once or AG

Inpatient 
Floxacins 
Ceftriaxone 
Cefepime 
Pip-tazo

May add AG pending culture results.

32
Q

AG uses

A

Reserved for serious illness

Amikacin reserved for multidrug resistance

pharma Omamah (4 decks)

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