STD Flashcards

1
Q

Preferred & alternative medicine for urogenital & anorectal infection ?

A

Preferred:
Single “high dose” IM ceftriaxone

Alternative:

  1. Other cephalosporins
  2. Azithromycin + gentamycin /gemefloxacin
  3. Spectinomycin
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2
Q

What is the adverse effect of combining azithromycin w/ gemefloxacin ?

A

QT prolongation

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3
Q

What do you give a patient with gonorrhea & chlamydia?

A

Add to gonorrhea treatment doxycycline for 7 days

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4
Q

What is the 1st line & alternatives for pharyngeal gonococcal infection

A

1st lime :
Single dose IM ceftriaxone

Alternative:
Azithromycin + gentamicin

Spectinomycin —> not used —> poor penetration

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5
Q

What is the 1st line intreating gonococcal conjunctivitis ?

A

Single 1g IM ceftriaxone

Topical FQ

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6
Q

If cornea was involved in gonococcal conjunctivitis what do you give the pt?

A

IV 1g ceftriaxone every 12-24 hrs

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7
Q

What do you give a patient w/Disseminated gonococcal infection (DGI)?

A

Ceftriaxone 1 g IV every 24 hours

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8
Q

What is used for prophylaxis (preferred & alternative)in infants born to mothers with gonorrhea?

A

Erythromycin ophthalmic ointment in single application

Alternative: ceftriaxone IM /IV once

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9
Q

Early sphyilis preferred

A

Penicillin G benzathine 2.4 million IM once

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10
Q

Early sphyilis alternative

A
  • Doxycycline or Tetracycline PO for 14 days
  • Ceftriaxone 1-2 g daily IM or IV for 10-14 days
  • Amoxicillin + probenecid , both given orally twice for 14 day
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11
Q

Late syphilis preferred

A

Penicillin G benzathine 2.4 million units IM once weekly for 3 weeks

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12
Q

Late sphyilis alternatives

A
  • Doxycycline orally twice daily for four weeks

* Ceftriaxone 2 g daily IM or IV for 10 -14 days

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13
Q

Neurosyphilis preferred

A

Aqueous penicillin G 3 to 4 million units IV every 4 hours for 10
to 14 days

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14
Q

Neurosyphilis alternative

A

Ceftriaxone 2 g IV daily for 10 to 14 days

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15
Q

Congenital sphyilis treatment ?

A

1 Aqueous penicillin G, IV, B.i.D

  1. procaine penicillin G IM as a single daily dose for 10 days
  2. Benzathine penicillin G, IM, single dose
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16
Q

1st line for chlamydia

A
  1. Doxycycline ( preferred if co-infection with N.gonorrhea )
  2. Azithromycin
17
Q

Doxycycline dose in chlamydia

A

100 mg twice daily for 7 days

18
Q

Dose of azithromycin in chlamydia

A

1g single dose

19
Q

Chlamydia alternatives

A
  1. Quinolones: ofloxacin orlevofloxacin for 7 days

2. Erythromycin & penicillin: less effective

20
Q

Quinolones cautions

A
  1. Avoid in pregnancy or lactation

2. Avoid inadolescents younger <18 years of age (bone abnormalities)

21
Q

Why is penicillin less effective in chlamydia

A

Bcz it can actually prolongate the presence of these pathogens ( they don’t die but they are in a state of stress as if it is dormant )

22
Q

Pregnant women chlamydia treatment

A

Azithromycin 1 g single dose OR amoxicillin or erythromycin (7-14 days)

23
Q

Newborn chlamydia mainfested as conjunctivitis & pneumonia treatment

A

Erythromycin 50 mg/kg orally in four divided doses for 14 days

• CAUTION: Both erythromycin & azithromycin could be associated with infantile hypertrophic pyloric stenosis (IHPS)

24
Q

Erythromycin is the choice in children with which disease

A

Gonorrhea & chlamydia

And erythromycin is preffered than azi

25
Q

Trichomoniasis treatment

A

5-nitromidazole drugs:

  1. Metronidazole
  2. Tinidazole

Dose: 500 mg PO BID for 7 days

26
Q

Trichomoniasis treatment caution

A
  1. Sex partners should be treated

2. Avoid intercourse until therapy completed

27
Q

HSV treatment

A

Oral therapy for 7 - 10 days

Acyclovir or valacyclovir or famciclovir

28
Q

When to start IV in HSV ?

A

More severe conds like CNS involvement or end organ disease including hepatitis or pneumonia

29
Q

What is IHPS

A

Infantile hypertrophic pyloric stenosis which happens in the tube connecting the stomach to intestine in which it closes so maybe the drug will be stopped or monitored