Uterotonic Drugs Flashcards

1
Q

Oxytocin mode of admin?

A

IV but no bolus

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2
Q

Oxytocin mechanism?

A

Increase intracellular Ca

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3
Q

Oxytocin side effects (4)?

A
  1. Nausea
  2. Flushing
  3. Tachycardia
  4. Hypotension
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4
Q

Oxytocin contraindications?

A
  1. Vasa previa

2. Cord prolapse

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5
Q

What is the trade name of Carboprost?

A

Hemabate

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6
Q

What is the mechanism of carboprost?

A

PG analog

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7
Q

What is the mode of admin for carboprost?

A

Injection

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8
Q

What are 2 side effects of carboprost?

A
  1. Nausea

2. Diarrhea

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9
Q

What are contraindications for carboprost?

A

Cardiac, pulmonary, renal, hepatic dz; acute PID

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10
Q

What is the trade name of methylergonovine?

A

Methergine

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11
Q

What is the mode of admin for methylergonovine?

A

IM, IV, or PO

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12
Q

What’s the mechanism of methylergonovine?

A

Binds 5-HT2A serotonin receptos leading to uterine SM contraction?

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13
Q

What are the negative side effects of methylergonovine (4)?

A
  1. HTN
  2. Headache
  3. MI
  4. Seizure
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14
Q

What’s are the 2 contraindications for methylergonovine?

A
  1. Pre-existing HTN

2. Pre-eclampsia

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15
Q

What’s the trade name for misoprostol?

A

Cytotec

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16
Q

What’s the mechanism of misoprostol?

A

PGE1 analog

17
Q

What are the side effects of misoprostol?

A

Diarrhea, abdominal pain

18
Q

What are the contraindications for misoprostol?

A

None really, but careful in asthmatic patients

19
Q

What is the trade name of dinoprostone?

A

Cervidil

20
Q

What’s the mechanism of dinoprostone?

A

PG

21
Q

What are the side effects of dinoprostone?

A

Nausea, vomiting, diarrhea, fever, back pain, flushing, tingly feeling, warmth in vagina, dizziness

22
Q

What are the contraindications for dinoprostone?

A

Cardiac, pulmonary, renal, hepatic dz; acute PID, concomitant IV oxytocin, h/o C-section, h/o major uterine surgery or difficult labor