USMLE Flashcards
clinical presentation and Ba swallow suggest achalasia.. what next?
endoscopy to r/o esophageal cancer
hordeolum is what?
a stye, usually caused by staph aureus
brain tumor with CT/MRI butterfly appearance
heterogenous and serpiginous contrast enhancement
GBM
target cells usually seen with what?
thalassemia, not so much iron deficiency anemia
what to do if you suspect toxic megacolon?
abd xray to confirm dx
how to tx toxic megacolon
conservative management: NPO, NG, steroids (if caused by IBD) or abx (if caused by infection)
-if that doesn’t work, then emergency surgery
patient with jaundice should be worked up with what dx test first?
US
recurrent bouts of upper abd pain, diarrhea/steatorrhea, weight loss
chronic pancreatitis
how to dx chronic pancreatitis
CT scan
amylase and lipase may be normal
if you suspect pancreatic cancer, what study should you get?
CT scan
arthralgias, weight loss, fever, diarrhea, abdominal pain, chronic cough, cardiac and valvular problems, pigmentation, lymphadenopathy
PAS positive stuff in lamina propria of small intestine
whipple’s disease
you are likely to form cholesterol gallstones during ______
pregnancy
effects of estrogen and progesterone
most common cause of iron deficiency anemia in old ppl is _________. what do you do next?
GI blood loss
perform colonoscopy. if negative, then EGD
asymptomatic diverticulosis is tx with what
increased fiber in the diet
- back pain, anemia, renal dysfunction, elevated ESR
- constipation, weakness, renal tubular problems, neurologic sxs, anorexia
multiple myeloma causing hypercalcemia
always look for __________ as a cause of constipation
hypercalcemia
old patients with new onset dyspepsia
young patients with new onset dyspepsia and weight loss/vomiting/dysphagia
what to do?
upper endoscopy
young pts with new onset dyspepsia and w/o alarm sxs. what to do? (2)
PPI trial
H Pylori testing
- old person with tea and toast diet is deficient in what
- macrocytic anemia
folic acid
vegans often deficient in what
anemia + CNS problems
vitamin B12
perifollicular hemorrhage, swollen gums, poor wound healing
scurvy (vitamin c deficiency)
osteomalacia and hypocalcemic tetany in adults caused by ______ deficiency
vitamin D
RBC fragility, hyporeflexia, muscle weakness, blindness caused by ______ deficiency
vitamin E
crypt abscesses are characteristic of ___________
ulcerative colitis
causes of bloody diarrhea
E Coli
Shigella
Campylobacter
explain the D-xylose test
normal: D-xylose is absorbed in the proximal small intestine and excreted in the urine
small intestine disease: D-xylose is not absorbed and instead, excreted via the feces
elevated BUN/Cr ratio means what (3 things)
- prerenal renal failure
- GI bleeding (due to reabsorption of blood from GI tract)
- steroid administration
first indicator of hypovolemia
pulse rate
post-prandial abdominal cramps, weakness, light-headedness, diaphoresis after having a partial gastrectomy
early dumping syndrome
how to tx early dumping syndrome
dietary modification
octreotide
reconstructive surgery
rectangular enveloped shaped crystals in urine
ca oxalate crystals
often due to ethylene glycol poisoning
how to calculated serum osmolarity
2*Na + glucose/18 + BUN/2.8
elevated osmolar gap metabolic acidosis indicates (3 things)
methanol, ethanol, or ethylene glycol poisoning
hypokalemia, hyponatremia with increased urinary Na and K
diuretic abuse
main causes of metabolic alkalosis
- administration of alkali
- removal of acidic gastric secretions via vomiting and NG tube
- renal H+ loss due to mineralocorticoid excess
- contraction alkalosis
in pts requiring multiple transfusions during surgery, they are at risk for _________
-hyperactive DTRs, muscle cramps, rarely convulsions
hypocalcemia
muscle weakness, cramps, flaccid paralysis, U waves on EKG
hypokalemia
muscle weakness, flaccid paralysis, peaked T waves, asystole
hyperkalemia
decreased DTRs, muscle paralysis, apnea, cardiac arrest
hypermagnesemia
causes of nephrogenic DI
hypercalcemia
severe hypokalemia
tubulointerstitial renal disease
meds: Li, amphotericin, cidofovir
common meds that cause hyperkalemia
nonselective beta blockers K sparing diuretics (ex. triamterene, trimethoprim) ACEIs ARBs NSAIDs digoxin cyclosporin heparin succinylcholine
glucose range for DKA
250-600
how to shift K from extracellular to intracellular
insulin and glucose
Na bicarb
albuterol (beta 2 agonist)
when not to use succinylcholine
when risk for hyperkalemia
- crush injuries
- demyelinating syndromes
- tumor lysis syndromes
potential side effects of loop diuretics
hypokalemia
metabolic alkalosis
prerenal renal failure
2 classes of metabolic alkalosis
- chloride sensitive (hypochloremic, saline responsive)
- urinary Cl < 20
- ECF volume depletion –> mineralocorticoid –> bicarb retention, H+ loss, K+ loss
- causes: thiazide/loop diuretics, vomiting/NG suction
- tx with volume repletion via saline - chloride resistant (normochloremic, saline unresponsive)
- urinary Cl > 20
- ECF volume expansion
- causes: primary hyperaldosteronism, Bartter’s, Gitelman’s, licorice ingestion
- not corrected by saline infusion
COPDers with chronic respiratory acidosis treated with diuretics are at risk for ______
prerenal renal failure due to drop in cardiac output
anorexia, fatigue, GI complaints, weight loss, hypotension, hyponatremia, hyperkalemia, hyper pigmentation or vitiligo, anemia, eosinophilia
Addison’s (adrenal insufficiency)
-causes: autoimmune, TB, HIV, fungi, metastatic cancer, hemorrhagic infarction
acute symptomatic hyponatremia: correct with ________ at no more than _______
3% saline
0.5 mEq/L/hr
pt with h/o GERD now has difficulty swallowing solids. endoscopy shows symmetric circumferential narrowing
peptic stricture
tissue transglutaminase antibodies are diagnostic of what?
celiac disease
mono-like syndrome consisting of fever, night sweats, LAD, arthralgias, and diarrhea should make you suspicious for ____
HIV
what is cryoprecipitate used for?
to treat patients with fibrinogen, vWF, or factor VIII deficiency
pRBC transfusion threshold
hgb < 7 for pts who are otherwise stable
hgb < 9 for unstable pts related to anemia or ACS with active ischemia
______ = dietary deficiency of niacin
often found in ppl with a ___-based diet in Asia
what are the 3 D’s?
pellagra
corn
3 Ds- diarrhea, dermatitis, dementia
SLE can cause diarrhea (t/f)
F